Amide bond cyclic peptide

Use high quality Fmoc Amino acids, using Fmoc Solid-phase synthesis process is used to obtain polypeptides with amide bonds forming rings, using HPLC The product was purified. The final product provides corresponding mass spectra and purity analysis. HPLC chromatogram, and COA.

Polypeptides with amide bonds forming a ring from head to tail,
Polypeptides with amide bond side chains forming a ring (Glu, Asp, Lys, Orn)

Case study of amide bond cyclic peptide synthesis
a. Cyclo (RGDfK): Cyclo (Arg-Gly-Asp-D-Phe-Lys)
b. Cyclo (RGDfV): Cyclo (Arg-Gly-Asp-D-Phe-Val)
c. Arg*-Gly-Asp-D-Phe-Val-Glu*-Gly-Asp-D-Phe-Val (Glu*and Arg*Amide bond forms a ring)
d. Arg-Gly-Asp-D-Phe-Val-Orn*-Gly-Asp-D-Phe-Val* (Orn*and Val*Amide bond forms a ring)