Peptide modification services
There are many contents for peptide labeling and peptide modification. Commonly used ones include N terminal marking or modification, N Terminal fluorescein modification, photosensitizer modification, N terminal fatty acid modification, C End labeling or modification, phosphorylation labeling, disulfide bond cyclization, lysine modification, high amino acid modification, PEG Modification, single labeling, double labeling, azide modification, Mal modification, N-Me Modification, coupling, etc. It is widely used in the research of peptide drugs, peptide biology, peptide antibodies and peptide reagents. Currently widely used are: Non-radioactive labeling ( C13,H2,N15), Fluorescent label ( FAM,FITC etc.), biotin labeling, phosphorylation modification, etc. Please call us for specific information:
| Detailed modification classification: | |
| C end tag technology |
C Terminal amidation (Amidation, C-termainal) |
| Aldehylation (Aldehydes) | |
| Alcoholylation (Alcohols) | |
| pNA (p-Nitroanilide) | |
| AMC | |
| AFC | |
| Mercaptoethyl amination (Cysteamide) | |
| Esterification (Ester) | |
| N- Alkylation (N-Alkyl Amides) | |
| N end tag technology | Acetylation Acetylated (Acetylated) |
| Palmytolyl | |
| HYNIC | |
| Biotin labeling (Biotinylated) | |
| Br Acetylation (Bromoacetylated) | |
| chelation reaction ( DOTA, DTPA conjugated) | |
| Formaldehyde (Formylated) | |
| Tetradecyl, octadecyl (Myristoylated) | |
| Succinylation, palmitic acidification, malic acidification, fatty acidation, etc. (Succinylated) | |
| Fluorescent label modification | C end modification: AFC, AMC, Dap(Dnp), Lys(Dye), pNA, Rh110 |
| N end modification: Bodipy-FL, Cy3, Cy5, Texas Red, 5-Tamra, 5-lodoacetamido fluorescein Rhodamine 110 and Rhodamine B Luciferin, EDANS FAM, FITC, MCA, Rox, Sulforhodamine 101, 5-TAMRA |
|
| cyclization reaction | Loops from beginning to end, loops from the middle, special loops ( N -> C or Head to Tail) |
| 2to disulfide bonds, 3 pairs of disulfide bonds (Disulfide (S-S bond formation). Trisulfide formation) | |
| Natural product active peptide cyclization (Cyclic-natural peptides ) | |
| Methylation modification | Side chain methylation Lys(For), Lys(Me), Lys(Me)2, Lys(Me)3, Arg(Me)2 symmetrical, D-Tyr(Me), D-Tyr(Et) |
| N Terminal methylation (N-Me-Arg, N-Me-Asp, N-Me-Glu, N-Me-Leu, N-Me-Nle, N-Me-Nva, N-Me-Phe, N-Me-S N- Me-Ser, N-Me-Trp, N-Me-Thr, N-Me-Val) | |
| Several special modifications | Various couplings (BSA, KLH conjugated peptides for antibody production) |
| Phosphorylation (Phosphoserine, Phosphothreonine, Phosphotyrosine) | |
| Sulfonated (Sulfated Tyrosine or Serine) | |
| MAPS (Multiple Antigenic Peptide) | |
| Glycopeptide (Glycopeptides) | |
| PEG Modify (PEGylation) | |
Source Peptide Company provides various modifications. The following is a quotation list for some modifications. It is for reference only. Corresponding discounts can be given according to the difficulty of the sequence. Please call us for specific information.
| 5 mg | 10 mg | 20 mg | |
| N-terminal modifications | |||
| N-Acetylation (Acetylation, free) | Free | Free | Free |
| N-Formylated (Formaldehyde, free) | Free | Free | Free |
| N-Myristoylated (Tetradecyl, octadecyl) | ￥200 | ￥300 | ￥400 |
| N-Succinylated (Succinylation, palmitylation, etc.) | ￥200 | ￥300 | ￥400 |
| N-Biotinlytion (N- Biotin labeling) | ￥300 | ￥500 | ￥800 |
| N-terminal Fatty acid (N- fatty acidification) | ￥200 | ￥300 | ￥500 |
| N-Rhodamine B (N- Rhodamine) | ￥400 | ￥500 | ￥800 |
| N-FITC, 5-FAM,6-FAM | ￥400 | ￥600 | ￥800 |
| N-Bromoacetylated (Br Acetylation) | ￥500 | ￥800 | ￥1000 |
| N-Alkyl Amides (Alkylation) | ￥500 | ￥800 | ￥1000 |
| DOTA, DTPA, Hynic conjugated (chelation reaction) | ￥800 | ￥1200 | ￥1600 |
| N-BODIPY,Cy3,Cy5 | Inquiry | Inquiry | Inquiry |
| C-terminal modifications | |||
| C-Amidation | Free | Free | Free |
| C-Aldehydes | ￥800 | ￥1200 | ￥1500 |
| C-Alcohols | ￥800 | ￥1200 | ￥1500 |
| C-Chloromethyl Ketones | ￥800 | ￥1200 | ￥1500 |
How to order