GRGDSPC CAS 91575-26-7

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GRGDSPC CAS 91575-26-7
Details
CAS Number: 91575-26-7
Sequence:
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Related documents
COA/MS/HPLC Report
Peptide Dissolution and Storage Guide
Category
Cell Adhesion Peptides
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Description

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Product name CAS:91575-26-7;GRGDSPC
Sequence  
Three letter sequence  
Peptide purity (HPLC, %) 95%/99%
Molecular formula C25H42N10O11S
Molecular weight (Da) 690.73

 

Product Basic Information Table

 

Product Standard English Name Product Abbreviation / Alias Function Tags (comma-separated) Amino Acid Full Name Sequence Molecular Formula Exact Molecular Weight (Da) Average Molecular Weight (Da) Terminal Modification - N-terminus Terminal Modification - C-terminus Sequence Length (aa)
GRGDSPC #GRGDSPC #Integrin binding peptide; #Cell adhesion peptide; #In vitro cell migration substrate Integrin receptor binding, cell adhesion regulation, cell migration, tumor invasion, angiogenesis, biomaterial surface modification Glycine-Arginine-Glycine-Aspartic acid-Serine-Proline-Cysteine C₂₉H₅₀N₁₄O₁₄S 846.3385 846.85 Unmodified Free carboxyl group 7

 

Physicochemical Solubility & Storage Parameters

 

Product Code Appearance Long-term Storage Conditions Short-term Storage Conditions Liquid Stability Solid Powder Stability
PEP-GRG01 White powder -20℃, light-proof sealed, nitrogen-filled aliquot packaging, avoid oxidation and repeated freeze-thaw 2-8℃, use within 1 month, prepare fresh before use Stable for 12 h at 4℃, prone to oxidation Stable for 3 years at -20℃ under nitrogen seal, 2 years at 4℃

 

Functional Description

 

Product Code Frontend Short Summary (for search list display) Detailed Biological Function Description Applicable Research Areas (comma-separated) Target / Receptor
PEP-GRG01 GRGDSPC contains classic RGD integrin recognition motif, C-terminal cysteine enables site-specific conjugation for cell adhesion, tumor metastasis and biomaterial modification research GRGDSPC is a heptapeptide carrying core RGD functional motif, which specifically binds cell membrane integrin α5β1 and αvβ3 receptors to competitively block cell adhesion to fibronectin and vitronectin. The C-terminal cysteine bears free thiol group for site-specific covalent conjugation with gold substrates, polymer materials and protein carriers. Widely applied in in vitro cell adhesion/migration assays, tumor invasion & metastasis mechanism research, angiogenesis inhibition, surface modification of tissue engineering scaffolds, integrin-targeted drug carrier screening, suitable for cell biology, tumor pharmacology and biomaterial engineering research Cell biology, integrin signaling pathway, tumor invasion & metastasis, angiogenesis, tissue engineering biomaterials, targeted carrier development Integrin αvβ3, α5β1, fibronectin, vitronectin, thiol-reactive biomaterials

 

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