Acetyl Tetrapeptide-15

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Acetyl Tetrapeptide-15
Details
•CAS: 928007-64-1
•Synonyms: Skinasensyl; Skinasensyl LS 9749
•Core structure: Acetylated tetrapeptide with sequence Ac-Tyr-Pro-Phe-Phe-NH₂, N-terminal acetylated, C-terminal amidated. A neurotransmitter inhibitor peptide that limits the release of pro-inflammatory neuromediators, reduces skin hyperreactivity, with soothing and anti-sensitive effects, suitable for sensitive skin, reported for use as a cosmetic ingredient.
•We also provide specifications from crude to 99% purity. Please contact us for details!

Related documents
•COA/MS/HPLC Report
•Peptide Dissolution and Storage Guide

Category
•Cosmetic bioactive peptide / Soothing anti-sensitive peptide / Neurotransmitter inhibitor peptide / Research tool peptide for cosmetic raw material
Category
Cosmetic Peptides
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Description

Shanghai Sonyt Biotechnology Co., Ltd. is one of the leading manufacturers and suppliers of acetyl tetrapeptide-15 in China, also supports custom service. Welcome to wholesale bulk high quality acetyl tetrapeptide-15 from our factory. Contact us for more details.

 

Description Acetyl tetrapeptide-15, trade name Skinasensyl, is an acetylated tetrapeptide composed of tyrosine, proline, and phenylalanine, N-terminal acetylated and C-terminal amidated. As a neurotransmitter inhibitor peptide, it acts on sensory neurons, limiting the release of pro-inflammatory neuromediators (such as substance P, calcitonin gene-related peptide CGRP, etc.), reducing skin hyperreactivity, thereby alleviating skin discomfort such as stinging, burning, and itching, and improving sensitive skin conditions. Studies demonstrate that it significantly reduces skin response to stimuli, improving skin comfort and tolerance. Widely used in soothing, anti-sensitive, repair skincare formulation development, and cosmetic mechanism research, especially suitable for sensitive skin and post-procedure repair products.
Peptide purity (HPLC) ≥98%
Molecular formula C₃₄H₃₉N₅O₆
Molecular weight (Da) 613.70
Structure type Linear modified tetrapeptide, N-terminal acetylated, C-terminal amidated, free peptide
Solubility Water soluble
Storage Sealed, protected from moisture and light

 

Product Basic Information Table

 

Product Standard English Name Product Abbreviation / Alias Function Tags (comma-separated) Core Structure Molecular Formula Exact Mass (Da) Average MW (Da) Salt Form Length (aa)
Acetyl tetrapeptide-15 Acetyl tetrapeptide-15; anti-aging repair tetrapeptide Anti-aging repair peptide, collagen & elastin synthesis promotion, skin laxity improvement, fine line reduction N-terminal acetylated linear tetrapeptide; acetylation end-capping improves peptide stability and skin tolerance, targets dermal fibroblasts to promote matrix protein synthesis C₂₂H₃₅N₅O₈ 497.25 ~497.5 Acetate 4

 

Physicochemical Solubility & Storage Parameters

 

Product Code Appearance Long-term Storage Short-term Storage Solution Stability Solid Powder Stability
PEP-ACT015 White powder Store at -20°C, sealed, dry and protected from light. Aliquot for storage. Stable for 1 month at 2–8°C in sealed dry condition; stable for shipping at ambient temperature. Stable for 7 days at 4°C. Acetylated tetrapeptide is freely soluble in water, dilute acetic acid and aqueous buffers. Acetylation end-capping improves enzymatic resistance with good stability at physiological pH. Stable for 2 years at -20°C, dry and protected from light.

 

Functional Description

 

Product Code Frontend Short Summary (for search list display) Detailed Biological Function Description Applicable Research Areas (comma-separated) Targets / Pathways
PEP-ACT015 Acetyl tetrapeptide-15 with high-stable acetylation boosts collagen & elastin synthesis for anti-aging Acetyl tetrapeptide-15 is a highly stable anti-aging tetrapeptide with acetylation modification. N-terminal acetylation end-capping significantly improves peptide enzymatic resistance and skin tolerance. It efficiently acts on dermal fibroblasts to synchronously promote the synthesis of type Ⅰ collagen and elastin, increases dermal thickness and elasticity, and improves skin laxity and static fine lines. It also has good formulation compatibility and can be widely used in various anti-aging, firming and repair skincare formulation systems. Skin anti-aging research, fibroblast function study, elastin regulation study, anti-wrinkle skincare product development, acetylated peptide application Fibroblast activation pathway; collagen-elastin synthesis regulatory pathway

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