Elamipretide Triacetate

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Elamipretide Triacetate
Details
CAS: 1849610-71-4
Aliases: MTP-131, SS-31
Core structure: Synthetic D-tetrapeptide mitochondrial protective agent, rich in aromatic cationic groups. It specifically binds to cardiolipin on the inner mitochondrial membrane, stabilizes mitochondrial membrane structure, improves mitochondrial respiratory function, reduces reactive oxygen species production, and exerts mitochondrial protective and antioxidant effects. Triacetate form significantly improves water solubility and formulation stability.
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Related documents
COA/MS/HPLC Report
Peptide Dissolution and Storage Guide
Category
Drug Peptides
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Description

Shanghai Sonyt Biotechnology Co., Ltd. is one of the leading manufacturers and suppliers of elamipretide triacetate in China, also supports custom service. Welcome to wholesale bulk high quality elamipretide triacetate from our factory. Contact us for more details.

 

Description Elamipretide is a classic mitochondria-targeted antioxidant protective peptide. By specifically binding to cardiolipin on the inner mitochondrial membrane, it stabilizes mitochondrial membrane structure and integrity, protects mitochondrial respiratory chain complex activity, improves mitochondrial oxidative phosphorylation efficiency, while reducing mitochondrial reactive oxygen species (ROS) production and inhibiting mitochondrial apoptotic pathways. It can penetrate the blood-brain barrier and myocardial cell membrane, and exhibits definite mitochondrial protection and function improvement effects in models of neurodegenerative diseases, heart failure, ischemia-reperfusion injury and aging-related diseases. It is an important tool peptide for mitochondrial biology research, mitochondrial disease drug development and anti-aging research.
Peptide purity (HPLC, %) 95%/98%/99%
Free peptide molecular formula C₃₃H₄₉N₇O₅
Free peptide molecular weight (Da) 627.8, higher for triacetate form
Structure type D-tetrapeptide, mitochondria-targeted structure, triacetate

 

Product Basic Information Table

 

Product Standard English Name Product Abbreviation / Alias Function Tags (comma-separated) Core Structure Molecular Formula Exact Mass (Da) Average MW (Da) Salt Form Length (aa)
Elamipretide triacetate Elamipretide triacetate; MTP-131 Mitochondrial protective peptide, cardiolipin binding, antioxidant & anti-aging D-tetrapeptide rich in aromatic cationic groups; targets cardiolipin on inner mitochondrial membrane to stabilize mitochondrial structure Free peptide: C₃₃H₄₉N₇O₅ 627.38 627.8 Triacetate 4 (D-amino acids)

 

Physicochemical Solubility & Storage Parameters

 

Product Code Appearance Long-term Storage Short-term Storage Solution Stability Solid Powder Stability
PEP-ELA001 White crystalline powder Store at -20°C, sealed and dry; also stable for short-term storage at room temperature. Stable for 3 months at 2–8°C in sealed dry condition; stable for shipping at ambient temperature. Stable for 14 days at 4°C. Triacetate salt is highly soluble in water and various buffers. D-peptide is resistant to enzymatic degradation with excellent solution stability, resistant to routine sterilization. Stable for 3 years at -20°C and 1 year at room temperature, dry condition.

 

Functional Description

 

Product Code Frontend Short Summary (for search list display) Detailed Biological Function Description Applicable Research Areas (comma-separated) Targets / Pathways
PEP-ELA001 D-type mitochondria-targeted tetrapeptide binds cardiolipin to protect mitochondria and improve energy metabolism Elamipretide is a classic mitochondria-targeted antioxidant protective peptide. By specifically binding to cardiolipin on the inner mitochondrial membrane, it stabilizes mitochondrial membrane structure and integrity, protects respiratory chain complex activity, improves mitochondrial oxidative phosphorylation efficiency, while reducing mitochondrial ROS production and inhibiting mitochondrial apoptotic pathways. It can penetrate the blood-brain barrier and myocardial cell membrane, with definite protective effects in neurodegenerative diseases, heart failure, ischemia-reperfusion injury and aging-related diseases. Mitochondrial biology research, neurodegenerative disease study, heart failure research, ischemia-reperfusion injury study, anti-aging research Inner mitochondrial membrane cardiolipin; Mitochondrial structure stabilization and oxidative stress regulatory pathway

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