Shanghai Sonyt Biotechnology Co., Ltd. is one of the leading manufacturers and suppliers of fitc-β-amyloid (25-35) in China, also supports custom service. Welcome to wholesale bulk high quality fitc-β-amyloid (25-35) from our factory. Contact us for more details.
| Description | Aβ25-35 is the minimal neurotoxic, aggregation-prone core of Aβ that retains aggregation, neurotoxicity and membrane-permeabilizing activity and aggregates faster than full-length Aβ. FITC labeling traces aggregation, cell binding and internalization in neuronal-toxicity, oxidative-stress and inhibitor-screening models. |
| Structure type | Linear 11-mer (Aβ25-35, FITC-labeled) |
| Solubility | Readily soluble in water/PBS; protect from light |
| Storage | Powder, −20°C, dry, light-protected |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| FITC-beta-Ala-Amyloid beta (25-35) | FITC-beta-Ala-Abeta(25-35); FITC-bAla-GSNKGAIIGLM | Amyloid-beta peptide,Abeta aggregation,FITC label,Alzheimer's disease,Neurotoxicity | FITC-betaAla-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-OH (FITC attached via beta-Ala spacer; Abeta 25-35 is an 11-mer) | C69H97N15O20S2 | 1519.65 | 1520.74 | TFA/Acetate (exchangeable upon request) | 11 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-FITCAb2535-01 | Yellow to orange-yellow powder (FITC-labeled, yellow/orange tint) | Store at -20 C, sealed, dry and light-protected (amber tube/foil); aliquot into single-use portions to avoid repeated freeze-thaw | ~1-2 weeks at 2-8 C, protected from light | Abeta(25-35), though short, is the most hydrophobic and strongly aggregating neurotoxic fragment; first dissolve in a small amount of DMSO/dilute ammonia, then dilute with PBS; aggregates/precipitates readily in solution-prepare fresh, protect from light against photobleaching | Solid powder: ~1-2 years at -20 C, sealed, dry and light-protected |
Functional Description
| Product Code | Frontend Short Summary | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-FITCAb2535-01 | FITC-labeled Abeta(25-35) neurotoxic hydrophobic-core fragment (beta-Ala spacer) for amyloid aggregation, AD models and fluorescence microscopy/flow studies | Abeta(25-35) (GSNKGAIIGLM) is the shortest hydrophobic core of beta-amyloid that retains the strongest neurotoxic and aggregation-prone properties; it spontaneously assembles into beta-sheet fibrils and induces neuronal apoptosis, making it a standard tool peptide for in vitro aggregation and neurotoxicity models of Alzheimer's disease (AD). FITC is attached at the N-terminus via a beta-alanine (beta-Ala) spacer to minimize labeling interference with aggregation, enabling direct use in aggregation-kinetics monitoring, confocal/fluorescence imaging, flow cytometry and aggregation-inhibitor screening. Must be kept light-protected at all times. | Alzheimer's disease (AD),Abeta aggregation/fibrillation,Neurotoxicity model,Fluorescence imaging,Aggregation-inhibitor screening | Amyloid-beta (Abeta); Abeta aggregation / beta-sheet; FITC fluorescence detection |
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