Shanghai Sonyt Biotechnology Co., Ltd. is one of the leading manufacturers and suppliers of bass hepcidin in China, also supports custom service. Welcome to wholesale bulk high quality bass hepcidin from our factory. Contact us for more details.
| Description | Bass hepcidin is a 21-residue antimicrobial peptide isolated from the gill of hybrid striped bass (Morone chrysops × Morone saxatilis) based on anti-E. coli activity; sequence GCRFCCNCCPNMSGCGVCCRF, containing eight cysteines forming four intramolecular disulfide bonds. Molecular formula C₈₆H₁₂₇N₂₉O₂₅S₉, MW 2255.69 Da. Bass hepcidin is a teleost member of the hepcidin family, highly homologous to human hepcidin-25, with a compact β-hairpin/cyclic structure and in vitro antibacterial activity against E. coli. Beyond innate immunity, fish hepcidins participate in iron homeostasis and antiviral responses. Bass hepcidin is a classic model for studying vertebrate hepcidin family evolution, dual antibacterial-iron-regulatory function, and fish innate immunity (PDB: 1S6W). |
| Structure type | Linear 21-mer (8 Cys forming 4 disulfide bonds, hepcidin cyclic peptide) |
| Solubility | Readily soluble in water, dilute acetic acid |
| Storage | Powder -20°C, dry, protected from light |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| Bass hepcidin | Bass hepcidin; fish hepcidin antimicrobial peptide | Hepcidin, antimicrobial peptide, iron metabolism regulation, innate immunity, disulfide-stabilized peptide | Iron-regulatory AMP expressed in bass liver, cysteine-rich, forming a stable hairpin via 4 intramolecular disulfide bonds; regulates systemic iron homeostasis and exerts broad-spectrum antibacterial activity | C₁₀₆H₁₃₅N₂₅O₂₃S₈ | 2725.72 | ~2727.8 | Free peptide | 25 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-BHEPC | White powder | Store at -20°C, sealed, dry and protected from light. Aliquot for storage. | Stable for 1 month at 2–8°C in sealed dry condition; stable for shipping at ambient temperature. | Stable for 7 days at 4°C. Soluble in dilute acetic acid and acidic buffers. 4 disulfide bonds form a highly stable conformation; protease-resistant and stable over a broad pH range. | Stable for 2 years at -20°C, dry and protected from light. |
Functional Description
| Product Code | Frontend Short Summary (for search list display) | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-BHEPC | Bass hepcidin with iron metabolism regulation and antibacterial activity | Bass hepcidin is an iron-regulatory AMP synthesized in bass liver, cysteine-rich, forming a highly stable hairpin conformation via 4 disulfide bonds. As a hepcidin, it regulates systemic iron absorption and release to maintain iron homeostasis. It also exerts broad-spectrum antibacterial and antifungal activities via membrane disruption, serving as a model for studying fish innate immunity and iron-immune crosstalk. | Iron metabolism research, fish innate immunity, antimicrobial peptides, hepcidin pathway, antifungal peptides | Iron regulatory pathway (Fpn/HAMP); bacterial membrane integrity; disulfide conformational stability |
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