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| Description | A 16-amino-acid peptide, sequence Ala-Pro-Val-Pro-Phe-Ser-Cys-Thr-Arg-Gly-Cys-Leu-Thr-His-Leu-Val (one-letter: APVPFSCTRGCLTHLV), containing two cysteine residues. Rich in proline and hydrophobic residues, it inhibits bacterial growth via membrane or intracellular-target mechanisms and is useful for novel antibacterial agent development. |
| Molecular formula | C₇₅H₁₂₁N₂₁O₂₀S₂ |
| Molecular weight (Da) | 1701.02 |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| LMW peptide | Low‑molecular‑weight antimicrobial peptide; LMW innate immune peptide | Antimicrobial peptide, broad‑spectrum antibacterial, endotoxin neutralization, immunomodulation, innate immunity | Natural low‑molecular‑weight cationic α‑helical antimicrobial peptide; exerts broad‑spectrum antibacterial activity by binding to bacterial membrane phospholipids and disrupting membrane integrity, neutralizes endotoxin LPS and inhibits TLR4‑mediated inflammatory response, with small molecular size and high tissue penetration | C₆₀H₁₀₅N₁₉O₁₀ | 1255.81 | ~1256.9 | Acetate | 12 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-LMW | White to off-white lyophilized powder | Store at -20°C, sealed, dry and protected from light. Aliquot for storage. | Stable for 1 month at 2–8°C in sealed dry condition; stable for shipping at ambient temperature. | Stable for 7 days at 4°C. Soluble in water, dilute acetic acid and PBS. Low-molecular-weight peptide with high tissue penetration; stable under acidic to neutral conditions, optimal endotoxin-binding activity at physiological pH. | Stable for 2 years at -20°C, dry and protected from light. |
Functional Description
| Product Code | Frontend Short Summary (for search list display) | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-LMW | LMW low-molecular-weight AMP with broad antibacterial and endotoxin-neutralizing activity | LMW peptide is a natural low-molecular-weight cationic antimicrobial peptide with small size and high tissue penetration. It binds anionic phospholipids on bacterial membranes to disrupt integrity for broad-spectrum activity, and efficiently neutralizes LPS endotoxin to suppress endotoxin-induced cytokine storm, widely used in sepsis and endotoxemia research. | Sepsis & endotoxin research, anti-infective drug development, immunomodulation research, innate immune peptides, tissue-penetrating peptides | Bacterial membrane permeability; LPS endotoxin neutralization; TLR4 pathway inhibition |
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