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| Product name | CAS:125366-42-9;Ac-MBP(1-11) |
| Sequence | Ac-ASQKRPSQRSK |
| Three letter sequence | Ac-Ala-Ser-Gln-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys |
| Peptide purity (HPLC, %) | 95%/99% |
| Molecular formula | C2H3K2OPS3 |
| Molecular weight (Da) | 248.41 |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Amino Acid Full Name Sequence | Molecular Formula | Exact Molecular Weight (Da) | Average Molecular Weight (Da) | Terminal Modification - N-terminus | Terminal Modification - C-terminus | Sequence Length (aa) |
| Ac-MBP(1-11) | #Ac-MBP1-11 #Myelin autoantigen peptide; #Multiple sclerosis autoepitope; #T cell activation research peptide | Autoimmune antigen, myelin basic protein epitope, multiple sclerosis model, CD4+ T cell activation, autoimmune inflammation, immune tolerance research | Acetyl-Serine-Serine-Lysine-Serine-Serine-Leucine-Serine-Arginine-Valine-Proline-Arginine | C₅₇H₁₀₄N₂₂O₂₄ | 1440.745 | 1441.56 | Acetylation modification | Free carboxyl group | 11 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage Conditions | Short-term Storage Conditions | Liquid Stability | Solid Powder Stability |
| PEP-MBP01 | White powder | -20℃, sealed away from light, aliquoted, avoid repeated freeze-thaw | 2-8℃, use within 1 month; prepare fresh before experiment | Stable for 24 h at 4℃ | 3 years at -20℃, 2 years at 4℃ |
Functional Description
| Product Code | Frontend Short Summary (for search list display) | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Target / Receptor |
| PEP-MBP01 | Acetylated MBP (1-11) is classic myelin autoimmunity epitope that induces specific CD4+ T cell response, used for constructing multiple sclerosis autoimmune pathological models | Ac-MBP(1-11) is an N-terminally acetylated immunodominant epitope of myelin basic protein. It is efficiently presented by MHC class II molecules and specifically activates myelin-reactive CD4+ helper T cells, triggering autoimmune inflammation in central nervous system. Served as standard antigen substrate for in vitro lymphocyte proliferation, cytokine secretion and autoantibody detection assays. Widely applied to research on multiple sclerosis pathogenesis, immune tolerance, in vitro screening of immunosuppressants and cell models for experimental autoimmune encephalomyelitis (EAE), suitable for autoimmune disease and neuroimmunology research | Neuroimmunology, autoimmune diseases, multiple sclerosis, myelin antigen epitope, CD4+ T cell activation, immunosuppressant screening | MHC class II molecules, CD4+ T cell receptor, MBP-specific autoantibodies |
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