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| Product name | CAS:265669-37-2;β-cateninpeptide |
| Sequence | RTYTYEKL |
| Three letter sequence | Arg-Thr-Tyr-Thr-Tyr-Glu-Lys-Leu |
| Peptide purity (HPLC, %) | 95%/99% |
| Molecular formula | C49H76N12O15 |
| Molecular weight (Da) | 1073.2 |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Amino Acid Full Name Sequence | Molecular Formula | Exact Molecular Weight (Da) | Average Molecular Weight (Da) | Terminal Modification - N-terminus | Terminal Modification - C-terminus | Sequence Length (aa) |
| β-catenin peptide | #β-catenin(1-19) #Wnt pathway peptide; #β-catenin binding substrate; #Tumor signaling research | Wnt/β-catenin pathway, cell adhesion, tumorigenesis, transcriptional co-activator, protein interaction, signal transduction | Alanine-Proline-Leucine-Serine-Serine-Threonine-Serine-Serine-Serine-Proline-Proline-Proline-Serine-Serine-Serine-Serine-Serine-Serine-Serine | C₈₅H₁₄₀N₂₈O₄₃ | 2172.965 | 2174.12 | Unmodified | Free carboxyl group | 19 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage Conditions | Short-term Storage Conditions | Liquid Stability | Solid Powder Stability |
| PEP-BCAT01 | White powder | -20℃, sealed away from light, aliquoted, avoid repeated freeze-thaw | 2-8℃, use within 1 month; prepare fresh before experiment | Stable for 24 h at 4℃ | 3 years at -20℃, 2 years at 4℃ |
Functional Description
| Product Code | Frontend Short Summary (for search list display) | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Target / Receptor |
| PEP-BCAT01 | β-catenin peptide is N-terminal functional fragment of β-catenin with multiple Ser/Thr phosphorylation sites, applied for canonical Wnt pathway and tumor signaling mechanism research | β-catenin peptide is a 19-residue N-terminal fragment of human β-catenin, enriched in Ser/Thr phosphorylation motifs recognized by glycogen synthase kinase GSK-3β. Unphosphorylated β-catenin translocates into nucleus to bind TCF/LEF transcription factors and activate Wnt target genes, regulating cell proliferation, migration and intercellular adhesion. Aberrant accumulation drives tumorigenesis including colorectal and hepatocellular carcinoma. It acts as classic in vitro substrate for GSK-3β kinase assay and model peptide for β-catenin/APC/Axin interaction study. Widely used for Wnt pathway inhibitor screening, tumor molecular mechanism, stem cell differentiation and cell adhesion cell models, suitable for tumor pharmacology and developmental biology research | Tumor biology, canonical Wnt signaling pathway, stem cell differentiation, protein kinase substrate, cell adhesion, anti-tumor drug screening | GSK-3β, APC, Axin, TCF/LEF transcription factors, β-catenin homo-oligomers |
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