CAS 157876-41-0 CEF19,Epstein-BarrViruslatentNA-3A(458-466)

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CAS 157876-41-0 CEF19,Epstein-BarrViruslatentNA-3A(458-466)
Details
EBV nuclear antigen-3A residues 458-466 from the CEF matrix;
Category: CEF pooled epitope / EBV latent-nuclear-antigen epitope.
Peptide Purity (HPLC) ≥95%
CAS No. 157876-41-0
Structure Linear 9-mer (EBNA-3A 458-466, CEF19)
Solubility Water/PBS
Storage Powder, −20°C, dry, light-protected
Category
Epitope Peptides
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Description

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Description EBNA-3A residues 458–466, one component of the CMV/EBV/influenza (CEF) memory-T pool, commonly recognized in healthy adults; used for cellular-immunity assessment and antiviral T monitoring.

 

Product Basic Information Table

 

Product Standard English Name Product Abbreviation / Alias Function Tags (comma-separated) Core Structure Molecular Formula Exact Mass (Da) Average MW (Da) Salt Form Length (aa)
CEF19, EBV EBNA-3A (458-466) CTL epitope peptide (HLA-B*35:01-restricted) CEF 19, EBV EBNA-3A 458-466, YPLHEQHGM peptide, HLA-B35 EBNA3A epitope viral T cell epitope, EBV, latent antigen, MHC class I ligand, CEF peptide pool, CTL recognition YPLHEQHGM (H-Tyr-Pro-Leu-His-Glu-Gln-His-Gly-Met-OH, linear 9-mer, free N-terminal amino / free C-terminal carboxyl) C49H70N14O14S 1110.49 1111.24 Free acid (per published formula) 9

 

Physicochemical Solubility & Storage Parameters

 

Product Code Appearance Long-term Storage Short-term Storage Solution Stability Solid Powder Stability
PEP-CEF19-01 white to off-white (MCE, purity ≥95% HPLC) Store frozen below -20 C, protected from light, dry and tightly sealed Store at 4 C sealed, dry and light-protected, use within 2-4 weeks; after reconstitution aliquot and store at -20 C, avoid repeated freeze-thaw Moderately soluble in water (~22% hydrophobic, polar E/D and K residues); contains 1 Met (oxidation-prone) and 1 Tyr (light-sensitive); after reconstitution protect from light, deoxygenate, avoid oxidants, and aliquot to reduce repeated freeze-thaw powder stable long-term at -20 C when dry, light-protected and sealed; keep moisture- and light-protected; Met is oxidation-sensitive, avoid prolonged air/light exposure

 

Functional Description

 

Product Code Frontend Short Summary Detailed Biological Function Description Applicable Research Areas (comma-separated) Targets / Receptors
PEP-CEF19-01 9-mer latent EBV EBNA-3A epitope (residues 458-466, YPLHEQHGM), HLA-B*35:01-restricted; component of the CEF T-cell control peptide pool. This 9-mer derives from residues 458-466 of the latent EBV nuclear antigen 3A (EBNA-3A, type-1 B95.8 strain) and is a well-characterized HLA-B*35:01-restricted CD8+ cytotoxic T-lymphocyte epitope; it is peptide #19 of the CEF (CMV/EBV/influenza) positive-control peptide pool. EBV-specific CD8+ T cells regulate EBV latent infection and EBV-associated malignancies, and this peptide is routinely used as a positive control in ELISPOT, intracellular cytokine staining and MHC tetramer T-cell assays. EBV immunology, CD8 T cell assays, CEF peptide pool, viral infection and cancer, immune monitoring positive control HLA-B*35:01 (EBNA-3A-specific CD8+ T cells)

 

 

 

 

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