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| Description | SEB residues 152–161 (TFA salt), which broadly activates T cells by crosslinking MHC-II with TCR Vβ; used for superantigen mechanisms and toxin neutralization. |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| SEB Domain (152-161) Peptide (TFA) | SEB 152-161 / KKKVTAQELD / mucosal transcytosis inhibitor peptide | Superantigen, SEB, mucosal transcytosis inhibition, CD28 costimulation, Staphylococcus aureus | H-Lys-Lys-Lys-Val-Thr-Ala-Gln-Glu-Leu-Asp-OH; derived from staphylococcal enterotoxin B (SEB) residues 152-161 (context 150-161 = TNKKKVTAQELD, β-strand 8/hinge/α-helix 4 region), the conserved mucosal-transcytosis epitope. Supplied as TFA salt (TFA salt formula C52H91N14O19F3, MW 1272.65/1273.37); free base C50H90N14O17 (MW 1158.66/1159.35). | C52H91N14O19F3 | 1272.65 | 1273.37 | TFA salt (per supplier CoA; free base MW 1158.66/1159.35) | 10 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-SEB152-01 | White to off-white powder (TFA salt form) | Store at -20°C, sealed, desiccated, ~36 months; TFA salt is hygroscopic - keep in a desiccator after opening | 2-8°C sealed, desiccated, ~2-4 weeks; after reconstitution aliquot and freeze at -20°C | Strongly cationic hydrophilic peptide (3 consecutive N-terminal Lys, 1 Glu + 1 Asp at C-terminus, net charge ~+1); readily soluble in water/PBS. Use aqueous solution within ~1 month when stored at -20°C | Hydrophilic peptide; store sealed and desiccated. No Cys/Met/Trp/Tyr/His - good solid-phase stability; protect TFA salt from moisture |
Functional Description
| Product Code | Frontend Short Summary | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Receptors |
| PEP-SEB152-01 | SEB 152-161 peptide, blocks superantigen mucosal transcytosis, CD28 costimulation modulator; TFA salt form. | A 10-mer from staphylococcal enterotoxin B (SEB), a superantigen toxin secreted by Staphylococcus aureus, residues 152-161 (β-strand 8/hinge/α-helix 4 region). This is the conserved mucosal-transcytosis epitope identified by Wang/Shupp et al. (Infect Immun 2002, PMID 11895985): the synthetic peptide KKKVTAQELD inhibits transcytosis of SEB (and related SEA/SEE/TSST-1) across intestinal epithelial monolayers by ~85%, blocking superantigen mucosal uptake; also studied as a CD28 costimulation modulator. | Microbiology, immunology, superantigen, mucosal immunity, anti-infection | Intestinal epithelial transcytosis pathway / CD28 costimulation |
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