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| Description | Human MAGE-A3 residues 271–279 (canonical HLA-A*0201 epitope FLWGPRALV), an important CD8+ T epitope in melanoma tumor rejection; used for cancer vaccines and ACT. |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| MAGE-3 (271-279) Peptide | MAGE-A3(271-279); FLWGPRALV; HLA-A2-restricted CTL epitope; cancer-testis antigen epitope | Tumor immunology, MAGE-A3 cancer-testis antigen, HLA-A2-restricted CTL epitope, melanoma, cancer vaccine | FLWGPRALV, linear free-acid 9-mer (N-term H, C-term OH) | C53H79N13O10 | 1057.61 | 1058.29 | TFA salt (per supplier COA) | 9 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-MAGE3B-01 | White to off-white powder | Store at -20°C, strictly protected from light, dry and sealed | Short-term storage at 2-8°C, protected from light | Highly hydrophobic: first dissolve in a small amount of DMSO, then dilute in water/buffer; light-sensitive (Trp, anti-oxidation), prepare fresh, avoid repeated freeze-thaw | Stable as light-protected powder |
Functional Description
| Product Code | Frontend Short Summary | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-MAGE3B-01 | The 9-mer FLWGPRALV spanning residues 271-279 of the human MAGE-A3 cancer-testis antigen, a canonical HLA-A2-restricted CTL epitope used in cancer vaccine and anti-tumor CTL research. | MAGE-3 (MAGE-A3) is a prototypical cancer-testis antigen expressed in melanoma and a wide range of epithelial tumors but silent in normal tissues except testis, making it a key target for cancer immunotherapy. The nonamer FLWGPRALV spanning residues 271-279 is a canonical HLA-A2 (HLA-A*0201)-restricted CD8+ cytotoxic T-lymphocyte epitope. It can stimulate patient PBMCs to generate specific CTLs in vitro and is recognized by cognate TCRs, and is used for MAGE-A3 vaccine design, CTL induction and detection, TCR-T / adoptive cell therapy and studies of anti-tumor immunity. | Tumor immunology, melanoma/solid tumors, cancer-testis antigens, CTL epitopes, cancer vaccines & adoptive cell therapy | MAGE-A3(271-279) epitope presented by HLA-A2 (HLA-A*0201); MAGE-A3-specific CD8+ T cells / TCR |
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