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| Product name | CAS:395069-92-8;MPG, HIV related |
| Sequence | GALFLGFLGAAGSTMGAWSQPKSKRKV |
| Three letter sequence | Gly-Ala-Leu-Phe-Leu-Gly-Phe-Leu-Gly-Ala-Ala-Gly-Ser-Thr-Met-Gly-Ala-Trp-Ser-Gln-Pro-Lys-Ser-Lys-Arg-Lys-Val |
| Peptide purity (HPLC, %) | 95%/99% |
| Molecular formula | C126H201N35O33S |
| Molecular weight (Da) | 2766.22 |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Amino Acid Full Name Sequence | Molecular Formula | Exact Molecular Weight (Da) | Average Molecular Weight (Da) | Terminal Modification - N-terminus | Terminal Modification - C-terminus | Sequence Length (aa) |
| MPG Peptide CAS 395069-92-8 | #MPG#, Amphipathic cell-penetrating peptide, HIV-derived membrane penetrating peptide, Nucleic acid delivery carrier peptide | Cell-penetrating peptide, Nucleic acid delivery, siRNA/plasmid vector, Gene delivery, HIV membrane fusion mechanism, Nuclear localization transport, Macromolecule intracellular delivery | Gly-Ala-Leu-Phe-Leu-Gly-Phe-Leu-Gly-Ala-Ala-Gly-Ser-Thr-Met-Gly-Ala-Trp-Ser-Gln-Lys-Lys-Lys-Arg-Lys-Val | C₁₂₆H₂₀₁N₃₅O₃₃S | 2766.22 | 2767.35 | Unmodified | Free carboxyl group | 27 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage Conditions | Short-term Storage Conditions | Liquid Stability | Solid Powder Stability |
| PEP-MPG001 | White powder | -20°C, sealed away from light, aliquot to avoid repeated freeze-thaw | 2-8°C, use within 1 month; prepare fresh before experiment | Stable for 18 h at 4°C | Stable for 2 years at -20°C under dry dark condition |
Functional Description
| Product Code | Frontend Short Summary (for search list display) | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Target / Receptor |
| PEP-MPG001 | 27aa classic amphipathic CPP, fused HIV-gp41 hydrophobic domain + SV40 NLS, efficiently delivers DNA/siRNA into cells and mediates nuclear transport | MPG peptide is a 27-residue amphipathic cell penetrating peptide. Its N-terminal fragment originates from HIV-1 gp41 hydrophobic membrane fusion domain, and C-terminal carries SV40 large T antigen nuclear localization signal (NLS). It combines transmembrane hydrophobicity and cationic nucleic acid binding capacity, can non-covalently bind plasmid DNA, siRNA, oligonucleotides and protein cargos; crosses plasma membrane independent of endocytosis and delivers cargos into cell nucleus. Widely applied in intracellular nucleic acid delivery, gene vector development, HIV membrane fusion mechanism research, live cell gene transfection, tumor gene therapy and peptide drug delivery | Molecular biology, Pharmaceutics, Gene delivery, Virology, Cell biology, Tumor pharmacology, Oligonucleotide therapeutics research | Cell membrane phospholipid bilayer, Nuclear transport protein, Nucleic acid phosphate backbone |
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