Angiotensin Ⅱ Human, FAM-labeled

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Angiotensin Ⅱ Human, FAM-labeled
Details
Core structure: Fluorescent peptide of human angiotensin Ⅱ octapeptide (Asp-Arg-Val-Tyr-Ile-His-Pro-Phe) site-specifically labeled with FAM (carboxyfluorescein), retains angiotensin receptor binding activity while emitting green fluorescence, for receptor binding, cell imaging and drug screening experiments
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COA/MS/HPLC Report
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Category
Fluorescent Labeled Peptide / Receptor Research Tool Peptide
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Pharmaceutical Peptides
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Description

Shanghai Sonyt Biotechnology Co., Ltd. is one of the leading manufacturers and suppliers of angiotensin ⅱ human, fam-labeled in China, also supports custom service. Welcome to wholesale bulk high quality angiotensin ⅱ human, fam-labeled from our factory. Contact us for more details.

 

Product name Angiotensin Ⅱ human, FAM‑labeled
Description This fluorescent peptide is a labeled tool peptide obtained by site‑specific conjugation of FAM fluorescent group at the N‑terminus of human angiotensin Ⅱ. It fully retains the binding activity of native angiotensin Ⅱ to AT1 and AT2 receptors, and can be quantitatively detected via the green fluorescence signal of FAM. It is widely used in research scenarios such as angiotensin receptor affinity determination, receptor binding competition assay, cell receptor endocytosis imaging, and high‑throughput screening of hypertension drugs. It is a classic fluorescent tool for the study of renin‑angiotensin system.
Peptide purity (HPLC, %) 95%/98%/99%
Free peptide molecular weight (Da) 1046.18, higher after labeling
Structure type Octapeptide N‑terminal FAM fluorescent labeling

 

Product Basic Information Table

 

Product Standard English Name Product Abbreviation / Alias Function Tags (comma-separated) Core Structure Molecular Formula Exact Mass (Da) Average MW (Da) Label Type Length (aa)
Angiotensin Ⅱ human, FAM-labeled FAM-labeled human Angiotensin Ⅱ; FAM-Ang Ⅱ Fluorescent labeled probe, Receptor binding assay, Cell imaging, Hypertension drug screening, AT receptor research, Tool peptide Human angiotensin Ⅱ octapeptide backbone with N-terminal covalently conjugated FAM fluorescein Labeled peptide macromolecule, subject to actual batch MS - ~1400 (theoretical) N-terminal FAM fluorescent labeling 8

 

Physicochemical Solubility & Storage Parameters

 

Product Code Appearance Long-term Storage Short-term Storage Solution Stability Solid Powder Stability
PEP-ANGF001 Yellow to orange-yellow powder Store at -20℃, sealed, dry & **strictly protected from light**, aliquoted; avoid repeated freeze-thaw cycles and light exposure Stable for 2 weeks at 2-8℃ sealed & protected from light; light-proof ice pack shipping recommended Stable for 7 days at 4℃ under light-proof conditions; fluorescence quenches rapidly under light and alkaline environment**Excellent water solubility, freely soluble in water and neutral physiological buffer**. FAM group sensitive to light and pH, fluorescence increases under alkaline condition but prone to quenching Stable for 1 year at -20℃ under dry & dark conditions

 

Functional Description

 

Product Code Frontend Short Summary (for search list display) Detailed Biological Function Description Applicable Research Areas (comma-separated) Targets / Pathways
PEP-ANGF001 Green fluorescent labeled angiotensin Ⅱ probe that retains receptor binding activity, for receptor binding and imaging research This labeled peptide retains the complete amino acid sequence and receptor binding activity of native angiotensin Ⅱ. It can specifically bind AT1 and AT2 receptors on the surface of tissue cells such as vascular smooth muscle, myocardium and kidney, while emitting stable green fluorescence via the N-terminal conjugated FAM group. It can be used in various experimental scenarios such as receptor-ligand affinity determination, competitive binding assay for screening receptor antagonists, live cell receptor tracing and endocytosis imaging, and flow cytometry quantification of receptor expression. It is a classic fluorescent tool for pharmacological research of renin-angiotensin system. Hypertension mechanism research, AT receptor pharmacology, Receptor binding assay, Cell fluorescence imaging, High-throughput drug screening, Fluorescent tool peptide Angiotensin AT1/AT2 receptors; FAM fluorescence tracing; Receptor-ligand interaction pathway

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