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| CAS | 524061-04-9 |
| Product name | CAS:524061-04-9:Riletamotide |
| Sequence | Ala-Glu-Arg-Leu-Thr-Ser-Arg-Val-Lys-Ala-Leu-Phe-Ser-Val-Leu |
| Three letter sequence | H-Ala-Glu-Arg-Leu-Thr-Ser-Arg-Val-Lys-Ala-Leu-Phe-Ser-Val-Leu-OH |
| Peptide purity (HPLC, %) | 95%/98%/99% |
| Molecular formula | C₇₆H₁₃₂N₂₂O₂₁ |
| Molecular weight (Da) | 1690.00 |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Amino Acid Full Name Sequence | Molecular Formula | Exact Molecular Weight (Da) | Average Molecular Weight (Da) | N-terminal Modification | C-terminal Modification | Sequence Length (aa) |
| Tapderimotide | Tapderimotide; hTERT (691-705); UV1 vaccine component; CAS 1221082-45-6 | Tumor antigen peptide,CTL epitope peptide,Active immunization activation,Telomerase targeting,Tumor vaccine development,UV1 vaccine component | Arginine-Threonine-Phenylalanine-Valine-Leucine-Arginine-Valine-Arginine-Alanine-Glutamine-Aspartic acid-Proline-Proline-Proline-Glutamic acid | C₇₉H₁₂₉N₂₅O₂₂ | 1780.97 | 1781.02 | Free amine, unmodified | Free carboxyl, unmodified | 15 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage Conditions | Short-term Storage Conditions | Liquid Stability | Solid Powder Stability |
| PEP-TAP001 | white powder | Store at -20℃, protected from light, sealed and dry, aliquoted; avoid repeated freeze-thaw cycles | Solid powder stable for 2 years sealed and dry at 2-8℃; prepare aqueous solutions freshly before use, aliquots stable for 1 month at -20℃ | Stable for 72 h at 4℃; contains multiple prolines and basic amino acids, avoid long-term storage at extreme pH | Stable for 3 years at -20℃ under dry & dark conditions |
Functional Description
| Product Code | Frontend Short Summary (for search list display) | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-TAP001 | hTERT 691-705 CTL epitope peptide, core component of UV1 tumor vaccine, targets and activates telomerase-specific T cell immunity | Tapderimotide is an HLA-restricted cytotoxic T lymphocyte (CTL) epitope peptide corresponding to amino acids 691 to 705 of human telomerase reverse transcriptase (hTERT), and is one of the three core antigen peptides of the UV1 telomerase-targeted vaccine. It can be uptaken and processed by antigen-presenting cells (APCs), presented on the cell surface via MHC class I molecules, and specifically activates hTERT-targeted CD8⁺ cytotoxic T cells, inducing their targeted killing of telomerase-positive tumor cells. Combined with Riletamotide and Alrefimotide from the same series, it can cover more HLA subtypes and improve the broad-spectrum immune response rate. Telomerase is highly expressed in over 85% of human tumors and serves as an ideal target for broad-spectrum tumor immunotherapy. This epitope peptide is widely used in peptide tumor vaccine development, tumor immunotherapy research, T cell activation mechanism research, and personalized tumor vaccine screening. | Tumor immunology research,Tumor vaccine development,T cell activation mechanism research,Telomerase targeting research,Immunotherapy combination research,CTL epitope screening | hTERT antigen epitope (691-705); MHC class I molecule presentation; CTL-mediated tumor cell killing pathway |
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