CAS:119260-99-0;Tetanustoxin(830-843)

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CAS:119260-99-0;Tetanustoxin(830-843)
Details
Tetanus toxin residues 830-843 universal helper epitope;
Category: Universal CD4 helper epitope / carrier peptide.
Peptide Purity (HPLC) ≥95%
CAS No. 119260-99-0
Structure Linear 14-mer (tetanus toxin 830-843, P2 helper)
Solubility Water, dilute acetic acid/PBS
Storage Powder, −20°C, dry, light-protected
Category
Epitope Peptides
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Description

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Description Tetanus toxoid residues 830–843 (the canonical P2 helper epitope), broadly recognized by HLA-DR CD4+ helper T cells; used as a carrier/adjuvant peptide to boost hapten or weak-antigen responses.

 

Product Basic Information Table

 

Product Standard English Name Product Abbreviation / Alias Function Tags (comma-separated) Core Structure Molecular Formula Exact Mass (Da) Average MW (Da) Salt Form Length (aa)
Tetanus Toxin (830-843) TT830-843; QYIKANSKFIGITE; p2 pan-HLA-DR Th epitope; CAS 119260-99-0 Tetanus toxin,universal Th epitope,pan-HLA-DR,vaccine carrier,CD4 T cells H-Gln-Tyr-Ile-Lys-Ala-Asn-Ser-Lys-Phe-Ile-Gly-Ile-Thr-Glu-OH (tetanus toxin heavy chain C-fragment residues 830-843; the classic 'p2' pan-HLA-DR universal Th epitope, a 14-mer version of the 830-844 p2 epitope lacking the C-terminal Leu; contains 1 Tyr - light protection) C74H118N18O22 1610.87 1611.86 Commonly supplied as free base or acetate (TargetMol TP1588 free base / TP1588L acetate); not specified on this listing - per COA 14

 

Physicochemical Solubility & Storage Parameters

 

Product Code Appearance Long-term Storage Short-term Storage Solution Stability Solid Powder Stability
PEP-TETX830-01 White to off-white powder Store at -20°C or below (recommended -20°C±5°C), dry, sealed, light-protected (contains 1 Tyr - prevent photo-oxidation); aliquot to avoid repeated freeze-thaw 2–8°C, sealed, dry and light-protected, use within 2-4 weeks; after reconstitution aliquot and store at -20°C; avoid repeated freeze-thaw Classically water-soluble Th peptide (2 Lys); dissolve directly in water or PBS, or pre-dissolve in a small volume of DMSO. Contains 1 Tyr (mildly light-sensitive) - protect solution from light. Prepare fresh; aliquot at -20°C; avoid repeated freeze-thaw powder stable for 2-3 years when dry, light-protected and sealed; protect from moisture; aliquot promptly after opening and keep with desiccant

 

Functional Description

 

Product Code Frontend Short Summary Detailed Biological Function Description Applicable Research Areas (comma-separated) Targets / Pathways
PEP-TETX830-01 Tetanus toxin 830-843 (QYIKANSKFIGITE), pan-HLA-DR universal Th helper epitope for vaccine design. A universal pan-HLA-DR T-helper (Th, classic 'p2') epitope derived from the C-fragment of the tetanus toxin (TeNT) heavy chain (residues 830-843). Widely used as a 'bystander' helper epitope in peptide vaccines to boost the immunogenicity of co-delivered B-cell or CD8+ CTL epitopes, and in human T-cell recall assays and vaccine-adjuvant activity assessment. Immunology,Vaccine development,T-helper epitopes,Tumor/infection immunology HLA-DR (multiple DR alleles, pan-DR restricted); CD4+ helper T cells

 

 

 

 

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