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| Description | Mouse gp100/Pmel17 residues 25–33 homolog (TFA salt), recognized by CD8+ T cells in B16 melanoma; used for B16 vaccines and ACT. |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| Gp100 (25-33), mouse (TFA) | mgp100 25-33; EGSRNQDWL; pme17 CTL epitope; CAS 212370-36-0 | melanoma,gp100 differentiation antigen,CD8+ T cells,CTL epitope,H-2Db,cancer vaccine,mouse model | Linear free-acid 9-mer H-Glu-Gly-Ser-Arg-Asn-Gln-Asp-Trp-Leu-OH (EGSRNQDWL), N-term H / C-term OH; residues 25-33 of the mouse self/tumor antigen glycoprotein gp100 (pme17); vs human gp100(25-33) (KVPRNQDWL): positions 1-3 differ (EGS vs KVP), positions 4-9 (RNQDWL) conserved; contains 1 Trp - protect from light; supplied as TFA salt (TFA salt formula C48H70N15O19F3, MW 1217.49/1218.17); free base C46H69N15O17 (MW 1103.50/1104.14, AnaSpec 1104.2 matches) | C48H70N15O19F3 | 1217.49 | 1218.17 | TFA salt (per supplier CoA; free base MW 1103.50/1104.14) | 9 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-GP100M-01 | White to off-white powder (TFA salt form) | Store at -20°C or below, strictly light-protected, dry and sealed (contains 1 Trp - prevent photo-oxidation); TFA salt is hygroscopic - keep in a desiccator after opening; aliquot to avoid repeated freeze-thaw | Store at 2-8°C, light-protected, dry and sealed, 2-4 weeks; after reconstitution aliquot and freeze at -20°C, light-protected | Contains Trp - keep solutions light-protected. Readily soluble in sterile water or buffer (many polar/charged residues); prepare fresh and avoid repeated freeze-thaw cycles | powder is stable; strictly light-protected due to Trp; protect TFA salt from moisture; keep sealed and dry |
Functional Description
| Product Code | Frontend Short Summary | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Receptors |
| PEP-GP100M-01 | A 9-mer spanning residues 25-33 of the mouse melanoma differentiation antigen gp100 (EGSRNQDWL); an H-2Db-restricted CD8+ CTL epitope used in mouse melanoma immunology and vaccine research; TFA salt form. | Gp100 (25-33), mouse (EGSRNQDWL) corresponds to residues 25-33 of the mouse self/tumor antigen glycoprotein gp100 (pme17) and is an H-2Db-restricted CD8+ cytotoxic T-lymphocyte (CTL) epitope. gp100 is a pigment-synthesis enzyme expressed on both normal melanocytes and melanoma cells, serving as a canonical tumor rejection/differentiation antigen in the mouse B16 melanoma model. This peptide is widely used for melanoma immunotherapy and vaccine research, epitope-specific CTL induction and detection, tetramer staining and adoptive T-cell therapy evaluation. | Tumor immunology,melanoma,CD8+ T-cell epitopes,mouse models,cancer vaccines | Mouse gp100/pme17 melanoma differentiation antigen; H-2Db-restricted CD8+ CTL epitope |
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