Shanghai Sonyt Biotechnology Co., Ltd. is one of the leading manufacturers and suppliers of ecamp3 (echinochloa crusgalli antimicrobial peptide 3) in China, also supports custom service. Welcome to wholesale bulk high quality ecamp3 (echinochloa crusgalli antimicrobial peptide 3) from our factory. Contact us for more details.
| Description | EcAMP3 (CAS: 2243219-65-8) is a hairpin-like plant antimicrobial peptide isolated from seeds of barnyard grass (Echinochloa crus-galli), molecular formula C172H282N72O57S6, MW 4430.91 Da. EcAMP3 belongs to the EcAMP precursor family characterized by a conserved seven-cysteine motif C1XXXC2(11-13)C3XXXC4, forming a double-stranded beta-sheet hairpin. EcAMP3 inhibits plant pathogenic fungi (e.g., Fusarium) and bacteria. The EcAMP family is homologous to plant alpha-hairpinin defense peptides, acting via membrane permeabilization and cell-wall interference. EcAMP3 is a tool for studying plant innate immunity and agricultural antimicrobial peptide development. |
| Structure type | Hairpin-like plant peptide (alpha-hairpinin family, seven-Cys motif, beta-sheet) |
| Solubility | Readily soluble in water, dilute acetic acid |
| Storage | Powder -20C, dry, protected from light |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| EcAMP3 (Echinochloa crusgalli antimicrobial peptide 3) | EcAMP3; EcAMP-3 | Antimicrobial peptide, plant defense peptide, α-hairpinin, antifungal, antibacterial, disulfide-stabilized, plant immunity | Linear 35-aa plant defense peptide (α-hairpinin family); 2 disulfide bonds (Cys5-Cys27, Cys9-Cys23) stabilize an α-helical hairpin; net charge +2 (10 Arg + 1 Lys − 3 Asp − 6 Glu); contains 1 Trp (Trp17) and 1 Met (Met25); highly hydrophilic surface, does not form canonical transmembrane pores; acts by binding fungal cell wall components then internalizing; from barnyard grass (Echinochloa crusgalli L.) seeds | C₁₇₂H₂₈₂N₇₂O₅₇S₅ (oxidized form, 2 disulfide bonds) | 4428.00 | 4430.92 | TFA salt (commercial standard) | 35 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-EcAMP3-01 | White powder | Store at -20°C, sealed, desiccated, protected from light. Contains 1 Met (oxidation-sensitive) and 1 Trp (light-sensitive); 2 disulfide bonds are reducing-agent-sensitive (avoid DTT/TCEP/β-ME). Recommend inert gas (Ar/N2) headspace. Aliquot to avoid repeated freeze-thaw. | 2–8°C for short-term use; working aliquots at -20°C or -80°C; stable for shipping at ambient. | Highly hydrophilic peptide-rich in Arg (10), Glu (6), and Asp (3); readily soluble in water/aqueous buffers (≥2–5 mg/mL), no organic co-solvent needed. KEY NOTE: The 2 disulfide bonds (Cys5-Cys27, Cys9-Cys23) are essential for the hairpin fold-any reducing agent (DTT, TCEP, β-ME) will disrupt them, causing unfolding and loss of activity. Contains 1 Met25 (oxidizes in solution) and 1 Trp17 (photo-oxidizes)-protect from light; prepare fresh or store aliquots at -80°C. Avoid strong oxidizers. | solid stable at -20°C, sealed, desiccated, protected from light. Hygroscopic. Long-term storage under inert gas recommended due to Met/Trp content. |
Functional Description
| Product Code | Frontend Short Summary (for search list display) | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-EcAMP3-01 | A 35-aa α-hairpin defense peptide isolated from barnyard grass (Echinochloa crusgalli) seeds, stabilized by 2 disulfide bonds, with both antifungal and antibacterial activity against phytopathogens; the first antibacterial member of the EcAMP family. | EcAMP3 is a plant defense peptide isolated from the seeds of barnyard grass (Echinochloa crusgalli L.), belonging to the α-hairpinin family. Unlike EcAMP1 (which is antifungal-only), EcAMP3 is the first family member with both antifungal and antibacterial activity. The peptide adopts a compact α-helical hairpin stabilized by 2 disulfide bonds (Cys5-Cys27, Cys9-Cys23). Unlike canonical membrane-active cationic peptides, EcAMP3 has a highly hydrophilic surface; its mechanism involves binding to fungal cell wall glycoproteins/amyloid components, followed by accumulation on the cell surface and internalization into the cytoplasm, inducing apoptosis-like cell death rather than direct membrane disruption. EcAMP3 inhibits both phytopathogenic fungi (Fusarium spp.) and phytopathogenic bacteria. This peptide is a valuable tool for studying plant innate immunity, defense peptide structure-activity relationships, and novel agricultural antimicrobial agents. | Plant innate immunity, antimicrobial peptide structure-activity, antifungal drugs, agricultural biocontrol, disulfide protein folding, agricultural antimicrobial development | Fungal cell wall glycoprotein/amyloid binding; cellular internalization; apoptosis-like cell death (non-lytic) |
Hot Tags: ecamp3 (echinochloa crusgalli antimicrobial peptide 3), China ecamp3 (echinochloa crusgalli antimicrobial peptide 3) manufacturers, suppliers, factory, 143459-88-5, 188713-80-6, antimicrobial peptides, CAS 143459 88 5, CAS 188713 80 6, CAS 79404 91 4
