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| Product name | CAS:2306406-71-1:Omramotide |
| Description | Omramotide is a highly selective somatostatin SSTR3 receptor agonist. Subtype specificity is achieved via unnatural amino acid substitution. It is applied in somatostatin receptor subtype functional identification, neuroendocrine tumor subtyping and central nervous regulation mechanism research. |
| Peptide purity (HPLC, %) | 95%/98%/99% |
| Molecular formula | C₆₁H₇₂N₁₂O₁₁S₂ |
| Molecular weight (Da) | 1205.44 |
| Terminal modification | C-terminal amidation |
Products Description
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Full Amino Acid Sequence | Molecular Formula | Exact Mass (Da) | Average MW (Da) | N-terminal Modification | C-terminal Modification | Sequence Length (aa) |
| Omramotide | Omramotide; SSTR3 selective agonist; CAS 2306406-71-1 | High-selectivity SSTR3 agonist,Somatostatin subtype study,Neuroendocrine tumor subtyping,Central nervous regulation,Cyclic peptide stability,Unnatural amino acid modification | D-Phenylalanine-cysteine-tyrosine-D-tryptophan-lysine-3-pyridylalanine-cysteine-threoninamide (cyclized via Cys2-Cys7 disulfide bridge) | C₆₁H₇₂N₁₂O₁₁S₂ | 1204.49 | 1205.44 | Free amine, D-amino acid configuration | Amidation | 8 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage Conditions | Short-term Storage Conditions | Liquid Stability | Solid Powder Stability |
| PEP-OMR001 | white powder | Store at -20℃, strictly protected from light, sealed and dry, aliquoted. **Strictly prohibited from strong reducing agents** | Solid powder stable for 2 years at 2-8℃ sealed and dry; small amount of DMSO can be added to stock solutions for solubilization | Stable for 72 h at 4℃; stable for 1 month at -20℃ in aliquots. **Slightly soluble in water, small amount of DMSO or dilute acetic acid required for solubilization**. Disulfide bridge is highly sensitive to reducing agents and prone to cleavage. Pyridine ring and aromatic residues are light-sensitive and easily degraded | Stable for 3 years at -20℃ under dry & dark conditions |
Functional Description
| Product Code | Frontend Short Summary (for search list display) | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-OMR001 | Highly selective SSTR3 agonist with strong subtype specificity, applied in somatostatin receptor subtype function and tumor subtyping research | Omramotide is a new-generation subtype-selective somatostatin analog. Introduction of 3-pyridylalanine substitution in the classic octapeptide cyclic backbone significantly alters receptor binding pocket matching, achieving highly selective agonism for SSTR3 receptor with extremely low affinity for other subtypes such as SSTR2 and SSTR5. SSTR3 activation inhibits adenylate cyclase, reduces intracellular cAMP levels, and mediates neurotransmitter release regulation, cell proliferation inhibition and other effects. This molecule serves as an exclusive tool peptide for somatostatin receptor subtype functional identification, neuroendocrine tumor receptor subtyping, and central nervous mood and cognition regulation research. It can be used to distinguish physiological and pathological effects mediated by different subtypes, and also as a lead molecule for subtype-targeted drug development. | Somatostatin subtype research,Neuroendocrine tumor subtyping,Central nervous regulation study,Receptor function identification,Subtype-selective drug development,Tumor signaling pathway research | Somatostatin Receptor 3 (SSTR3); cAMP/PKA signaling pathway; Neurotransmitter release regulatory pathway |
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