CAS 33103-22-9 Enviomycin

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CAS 33103-22-9 Enviomycin
Details
CAS: 33103-22-9
Core structure: Basic cyclic peptide antituberculous antibiotic with multiple unnatural amino acids and guanidino modifications, tuberactinomycin N
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Related documents
COA/MS/HPLC Report
Peptide Dissolution and Storage Guide
Category
Polypeptide Antibiotic / Anti-mycobacterial Cyclic Peptide
Category
Pharmaceutical Peptides
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Description

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Product name CAS:33103‑22‑9 Enviomycin
Description Enviomycin is a cyclic peptide antituberculous antibiotic derived from Actinomycetes. It exerts bacteriostatic effect by inhibiting protein synthesis of Mycobacterium tuberculosis, and remains active against streptomycin‑resistant tuberculosis strains. Applied in drug‑resistant tuberculosis research, anti‑tuberculosis drug screening and microbial pharmacology mechanism research.
Purity (HPLC, %) 90%/95%/98%
Molecular formula C₇₄H₁₀₈N₂₆O₂₀
Molecular weight (Da) 1681.82
Structure type Basic cyclic peptide antibiotic with unnatural amino acids such as β‑lysine

 

Products Description

 

Product Standard English Name Product Abbreviation / Alias Function Tags (comma-separated) Core Structure Molecular Formula Exact Mass (Da) Average MW (Da) Cyclization Mode Structure Type
Enviomycin Enviomycin; Tuberactinomycin N; CAS 33103-22-9 Anti-tuberculosis activity,Drug-resistant mycobacteria,Cyclic peptide antibiotic,Protein synthesis inhibition,Tuberculosis drug screening,Microbial pharmacology Multi-component basic cyclic peptide backbone with β-amino acids, guanidino groups and unsaturated bonds C₇₄H₁₀₈N₂₆O₂₀ 1680.82 1681.82 Peptide bond macrocyclization Non-ribosomal cyclic peptide antibiotic

 

Physicochemical Solubility & Storage Parameters

 

Product Code Appearance Long-term Storage Conditions Short-term Storage Conditions Liquid Stability Solid Powder Stability
PEP-ENV001 white powder Store at -20℃, sealed, dry & protected from light, aliquoted; avoid high temperature, humidity and acid/base Solid powder stable for 2 years at 2-8℃ sealed and dry; stock solutions prepared in dilute aqueous acid Stable for 72 h at 4℃ under acidic conditions; rapidly degraded under neutral and alkaline conditions. **Moderate water solubility, freely soluble in dilute acetic acid and dilute hydrochloric acid, limited solubility in water**. Activity rapidly lost in alkaline environment. Hygroscopic, strictly sealed for moisture protection Stable for 2 years at -20℃ under dry & dark conditions

 

Functional Description

 

Product Code Frontend Short Summary (for search list display) Detailed Biological Function Description Applicable Research Areas (comma-separated) Targets / Pathways
PEP-ENV001 Cyclic peptide antituberculous antibiotic that inhibits mycobacterial protein synthesis, effective against streptomycin-resistant strains Enviomycin is a natural basic cyclic peptide antibiotic produced by Streptomyces fermentation, belonging to the tuberactinomycin family. It has a macrocyclic peptide structure with multiple unnatural amino acids, rich in basic guanidino groups. It specifically binds to the 30S subunit of Mycobacterium tuberculosis ribosomes, interferes with peptidyl transferase activity, inhibits protein synthesis, and thus suppresses mycobacterial growth and reproduction. This molecule exhibits bacteriostatic activity against Mycobacterium tuberculosis hominis and Mycobacterium bovis, and has no cross-resistance with streptomycin, remaining effective against streptomycin-resistant strains. It is mainly used in pharmacological research of drug-resistant tuberculosis, anti-tuberculosis new drug screening and evaluation, microbial protein synthesis mechanism, and ribosome function research, serving as a tool molecule for drug-resistant tuberculosis research and novel antibiotic development. Drug-resistant tuberculosis research,Anti-tuberculosis drug development,Microbial protein synthesis study,Ribosome function research,Mycobacterial biology,Antibiotic pharmacology research Bacterial ribosome 30S subunit; Peptidyl transferase inhibition; Mycobacterial protein synthesis blockade pathway

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