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| Description | A Q4 mutant of the canonical OVA CD8 epitope SIINFEKL, used to probe anchor-residue effects on H-2Kb presentation and TCR activation; a standard model for immunogenicity. |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| OVA-Q4 Peptide | OVA-Q4 Peptide, OVA257-264 (SIINFEKL) N4Q variant, SIIQFEKL, CAS 148274-85-5 | Model antigen peptide, H-2Kb-restricted, CD8+ T cell epitope, OVA variant, Vaccine immunology | SIIQFEKL (H-Ser-Ile-Ile-Gln-Phe-Glu-Lys-Leu-OH, linear 8-mer, free N/C termini) | C46H76N10O13 | 976.56 | 977.17 | TFA salt (typical) (commonly sold as TFA salt) | 8 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-OVAQ4-01 | White to off-white powder (listed as solid by MCE) | Store frozen below -20°C, sealed, dry and protected from light; avoid repeated freeze-thaw cycles | Store sealed and dry at 4°C, use within 2-4 weeks; aliquot and store reconstituted solution at -20°C | Contains hydrophobic residues (Ile x2 / Phe / Leu), net charge 0: prepare a stock solution in DMSO first, then dilute with water or buffer to working concentration | powder is stable sealed, dry and light-protected at -20°C; protect from moisture |
Functional Description
| Product Code | Frontend Short Summary | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-OVAQ4-01 | The Asn4->Gln variant SIIQFEKL of chicken ovalbumin OVA257-264 (SIINFEKL); an 8-mer H-2Kb-restricted CD8+ T cell epitope analogue, CAS 148274-85-5 | This is the single N4->Q variant (sequence SIIQFEKL, 8-mer) of the canonical H-2Kb-restricted CD8+ T cell epitope OVA257-264 (SIINFEKL) from chicken ovalbumin. SIINFEKL is the model antigen epitope recognized by the OT-I transgenic TCR; the Q4 variant retains H-2Kb binding and OT-I T cell recognition and is widely used for antigen-specific CD8+ T cell responses, vaccines and immune-mechanism studies. MCE lists CAS 148274-85-5, formula C46H76N10O13 and MW ~977.15, consistent with our residue-wise calculation (exact 976.56 / average 977.17). | Tumor immunology, Vaccine development, CD8+ T cell detection, Model antigen, Immune mechanisms | H-2Kb (MHC-I presentation); OT-I T cell receptor (TCR) |
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