CAS 149997-91-1 HSV-gB2(498-505)

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CAS 149997-91-1 HSV-gB2(498-505)
Details
HSV-2 glycoprotein B residues 498-505;
Category: Herpesvirus glycoprotein / HSV CTL epitope.
Peptide Purity (HPLC) ≥95%
CAS No. 149997-91-1
Structure Linear 8-mer (HSV-gB2 498-505, H-2Kb)
Solubility Water, DMSO cosolvent, PBS
Storage Powder, −20°C, dry, light-protected
Category
Epitope Peptides
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Description

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Description HSV-2 gB residues 498–505, an H-2Kb-restricted CD8+ T epitope; used for HSV infection models, mucosal immunity and vaccines.

 

Product Basic Information Table

 

Product Standard English Name Product Abbreviation / Alias Function Tags (comma-separated) Core Structure Molecular Formula Exact Mass (Da) Average MW (Da) Salt Form Length (aa)
HSV-gB2 (498-505) Peptide (gB-8p) HSV gB 498-505 / SSIEFARL / H-2Kb CTL epitope HSV, herpes simplex virus, CD8+ CTL epitope, H-2Kb restricted, HSV-2 vaccine H-Ser-Ser-Ile-Glu-Phe-Ala-Arg-Leu-OH; derived from HSV-1/HSV-2 glycoprotein B (gB/gB2) residues 498-505; the mouse MHC-I H-2Kb-restricted immunodominant CD8+ T-cell epitope. C41H67N11O13 921.49 922.05 Free peptide 8

 

Physicochemical Solubility & Storage Parameters

 

Product Code Appearance Long-term Storage Short-term Storage Solution Stability Solid Powder Stability
PEP-HSVGB2-01 White to off-white powder Store at -20°C, sealed, desiccated, protected from light 2-8°C sealed, desiccated, ~2-4 weeks Hydrophilic/amphipathic peptide (1 Phe, 1 Arg, 1 Glu, 2 Ser); soluble in water/PBS. Prepare fresh No Cys/Met/Trp/Tyr; stable when sealed and desiccated

 

Functional Description

 

Product Code Frontend Short Summary Detailed Biological Function Description Applicable Research Areas (comma-separated) Targets / Pathways
PEP-HSVGB2-01 HSV gB 498-505 H-2Kb immunodominant CD8 epitope, tool peptide for HSV-2 vaccine research An 8-mer immunodominant CD8+ CTL epitope from herpes simplex virus (HSV-1/HSV-2) glycoprotein B residues 498-505, sequence SSIEFARL. Presented by mouse MHC-I H-2Kb (C57BL/6, H-2b haplotype); the dominant CD8 target in mouse HSV infection. Widely used as the antigenic peptide in prophylactic/therapeutic genital HSV-2 vaccine studies (CpG-peptide, palmitoylated PADRE-gB lipopeptide, adenovirus prime/boost) in the B6 model. Immunology, virology, vaccine development, T-cell epitope, HSV-2 H-2Kb (MHC-I, C57BL/6)

 

 

 

 

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