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| Description | Human MAGE-A3 residues 195–203, an HLA-restricted CD8+ T epitope; MAGE-A3 is silent/activated in tumors but not normal testis tissue, a tumor-specific rejection antigen; used for vaccines and immunotherapy. |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| MAGE-A3 (195-203) | MAGE-A3 195-203; IMPKAGLLI; MAGE-A3 (195-203) peptide; melanoma antigen 3 epitope; CAS 171066-85-6 | Cancer immunotherapy,Peptide vaccines,In-vitro CTL induction,HLA-A24 epitopes,MAGE-A3-positive tumor research,HLA-A*2402 | H-Ile-Met-Pro-Lys-Ala-Gly-Leu-Leu-Ile-OH; residues 195-203 of human MAGE-A3 cancer-testis antigen (UniProt P43357), an HLA-A*2402-restricted CTL epitope originally identified in the MZ2-MEL melanoma line MZ2-D; linear peptide with free N-terminal amine / free C-terminal carboxyl; 7/9 residues hydrophobic; contains 1 Met-protect from oxidation. | C45H82N10O10S | 954.59 | 955.27 | TFA salt (free acid / acetate available on request; per COA) | 9 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-MAGEA3195-01 | White to off-white powder. | -20°C, dry, sealed, light-protected; contains Met, recommend nitrogen purge/deoxygenation to prevent oxidation; avoid repeated freeze-thaw. | 2-8°C, dry and light-protected; use within 1 week. | Strongly hydrophobic 9-mer: first dissolve in a small amount of DMSO to a 5-10 mg/mL stock, then dilute with sterile water/PBS; store stock in aliquots at -20°C; deoxygenate solution (contains Met); prepare fresh. | powder is stable ~1-2 years at -20°C dry and light-protected; protect from moisture and oxidation (contains Met). |
Functional Description
| Product Code | Frontend Short Summary | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-MAGEA3195-01 | MAGE-A3 195-203 HLA-A*2402-restricted 9-mer IMPKAGLLI for tumor CTL and peptide-vaccine research. | MAGE-A3 is a cancer-testis antigen aberrantly expressed in many tumors. The 9-mer IMPKAGLLI (residues 195-203) is presented by HLA-A*2402 and induces specific CTLs that lyse MAGE-A3-positive tumor cells; a classic epitope for peptide-vaccine and in-vitro CTL induction studies in HLA-A24-positive cancer patients. | Cancer immunotherapy,Peptide vaccines,In-vitro CTL induction,HLA-A24 epitopes,MAGE-A3-positive tumor research | MAGE-A3 epitope presented by HLA-A*2402 (MHC class I); CD8+ T-cell TCR |
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