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| Description | Human MAGE-A3 residues 167–176 (canonical HLA-A1 epitope EADPTGHSY), one of the first tumor-specific rejection epitopes; used for cancer vaccines, CTL responses and ACT. |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| Human MAGE-A3 Antigen (167-176) HLA-B44 epitope peptide | MAGE-3 (167-176); MEVDPIGHLY; MAGE-A3 HLA-B44 epitope | cancer-testis antigen,MAGE-A3,melanoma,CD8+ T cells,HLA-B44,cancer vaccine,tumor immunology | Linear free-acid 10-mer MEVDPIGHLY (N-term H / C-term OH) | C53H80N12O16S | 1172.55 | 1173.35 | TFA salt (per supplier CoA) | 10 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-MAGE3A-01 | White to off-white powder | Store at -20°C or below, protected from light, dry and sealed | Store at 2-8°C, protected from light and moisture, for 2-4 weeks | Contains oxidation-prone Met and light-sensitive Tyr; dissolve in sterile water or buffer, prepare fresh, avoid oxidants and repeated freeze-thaw cycles | powder is stable; protect from light, keep sealed and dry |
Functional Description
| Product Code | Frontend Short Summary | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-MAGE3A-01 | A 10-mer spanning residues 167-176 of human MAGE-A3 (MEVDPIGHLY), an HLA-B44-restricted T-cell epitope used in cancer vaccines and tumor-specific T-cell research. | MAGE-3 Antigen (167-176) (MEVDPIGHLY) is a 10-mer from residues 167-176 of the human melanoma-encoded cancer-testis antigen MAGE-A3 and serves as an HLA-B44 (HLA-B*44)-restricted T-cell epitope; its C-terminal 9-mer EVDPIGHLY (168-176) is the well-known HLA-A1-restricted CTL epitope. MAGE-A3 is expressed in a variety of tumors (including melanoma) but not in normal tissues except testis, making it a key target for cancer immunotherapy and vaccination. This peptide is used for detecting MAGE-A3-specific CD8+ T-cell responses, epitope mapping, cancer-vaccine immunogen design and adoptive T-cell therapy studies. | Tumor immunology,melanoma,cancer vaccines,CD8+ T-cell epitopes,cancer-testis antigens | Human MAGE-A3 (MAGE-3) cancer-testis antigen; HLA-B44-restricted (168-176 EVDPIGHLY is HLA-A1) T-cell epitope |
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