CAS 189323-64-6 HBVSeq1aa:63-71

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CAS 189323-64-6 HBVSeq1aa:63-71
Details
Hepatitis B virus sequence-1 residues 63-71 epitope;
Category: HBV antigen epitope / hepatitis-B CTL epitope.
Peptide Purity (HPLC) ≥95%
CAS No. 189323-64-6
Structure Linear 9-mer (HBV Seq1 63-71)
Solubility Water/PBS
Storage Powder, −20°C, dry, light-protected
Category
Epitope Peptides
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Description

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Description HBV sequence-1 residues 63–71, an HLA-restricted CD8+ T epitope; used for HBV-specific CTL responses, viral clearance and chronic-hepatitis-B therapeutic vaccines.

 

Product Basic Information Table

 

Product Standard English Name Product Abbreviation / Alias Function Tags (comma-separated) Core Structure Molecular Formula Exact Mass (Da) Average MW (Da) Salt Form Length (aa)
HBV Seq1 aa:63-71 HBV Seq1 aa:63-71; GELMTLATW HBV, HBcAg, CTL epitope, antiviral immunity, 9-mer peptide H-Gly-Glu-Leu-Met-Thr-Leu-Ala-Thr-Trp-OH C46H72N10O14S 1020.5 1021.2 以供应商COA为准(常用TFA盐) 9

 

Physicochemical Solubility & Storage Parameters

 

Product Code Appearance Long-term Storage Short-term Storage Solution Stability Solid Powder Stability
PEP-HBVC63-01 White to off-white powder -20 °C, dry, protected from light, sealed storage; nitrogen flush preferred. 2–8 °C short-term; aliquot working solutions and store frozen at -20 °C. Contains Met (position 4), which oxidizes readily, and Trp (position 9), which is light-sensitive and prone to oxidation/degradation; strongly hydrophobic (enriched in L/A/V/T/W) with poor water solubility, requiring DMSO-assisted dissolution with sonication. Prepare fresh, protect from light and flush with inert gas. Relatively stable as powder under dry, sealed, light-protected, nitrogen-flushed conditions.

 

Functional Description

 

Product Code Frontend Short Summary Detailed Biological Function Description Applicable Research Areas (comma-separated) Targets / Receptors
PEP-HBVC63-01 9-mer CTL epitope from hepatitis B virus core protein (HBcAg) residues 63–71, for HBV-specific CD8+ T-cell immunity studies. The 9-mer from HBV core antigen (HBcAg/Capsid protein) residues 63–71 is an epitope recognized by HBV-specific CD8+ cytotoxic T lymphocytes (CTLs). Used for immune-status assessment in chronic hepatitis B, HBV vaccine development, therapeutic vaccines, T-cell response monitoring (ELISpot/tetramer) and studies of viral clearance mechanisms. The commercial sequence GELMTLATW differs from the UniProt P03147 isolate GDLMTLATW by a D/E genotype polymorphism at position 64. Hepatitis B; HBcAg; CTL epitope; therapeutic vaccine; viral immunity MHC class I (CD8+ T-cell epitope)

 

 

 

 

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