CAS 145253-17-4 InfluenzaANP(366-374)

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CAS 145253-17-4 InfluenzaANP(366-374)
Details
Influenza A nucleoprotein residues 366-374 epitope;
Category: Influenza NP conserved CTL epitope / cross-strain peptide.
Peptide Purity (HPLC) ≥95%
CAS No. 145253-17-4
Structure Linear 9-mer (influenza A NP 366-374)
Solubility Water/PBS
Storage Powder, −20°C, dry, light-protected
Category
Epitope Peptides
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Description

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Description Influenza A NP residues 366–374 (e.g. ASNENMDAM, a canonical H-2Db-restricted epitope), highly conserved across influenza A strains; used for cross-protective CD8+ responses and universal vaccines.

 

Product Basic Information Table

 

Product Standard English Name Product Abbreviation / Alias Function Tags (comma-separated) Core Structure Molecular Formula Exact Mass (Da) Average MW (Da) Salt Form Length (aa)
Influenza A virus NP (366-374) CTL epitope peptide (strain A/NT/60/68, H-2Db-restricted) Influenza A NP 366-374, ASNENMETM peptide, NP366 PR8 epitope, H-2Db influenza CTL epitope influenza CTL epitope, nucleoprotein, MHC class I ligand, H-2Db, CD8 T cell epitope, viral immunity ASNENMDAM (H-Ala-Ser-Asn-Glu-Asn-Met-Asp-Ala-Met-OH, linear 9-mer, free N-terminal amino / free C-terminal carboxyl) C36H59N11O17S2 981.35 982.05 Free acid (per published formula) 9

 

Physicochemical Solubility & Storage Parameters

 

Product Code Appearance Long-term Storage Short-term Storage Solution Stability Solid Powder Stability
PEP-NP366-01 white to off-white (MCE, purity ≥95% HPLC) Store frozen below -20 C, dry and tightly sealed Store at 4 C sealed and dry, use within 2-4 weeks; after reconstitution aliquot and store at -20 C, avoid repeated freeze-thaw Freely soluble in water (~33% hydrophobic); contains 2 Met (oxidation-prone); after reconstitution deoxygenate, avoid oxidants and repeated freeze-thaw; no Trp/Tyr/Cys, no special light-protection requirement powder stable long-term at -20 C when dry and sealed; keep moisture-proof; Met is oxidation-sensitive, avoid prolonged air exposure

 

Functional Description

 

Product Code Frontend Short Summary Detailed Biological Function Description Applicable Research Areas (comma-separated) Targets / Receptors
PEP-NP366-01 Prototypical 9-mer influenza A nucleoprotein CTL epitope (366-374, ASNENMETM), immunodominant H-2Db-restricted CD8 epitope in mice. This 9-mer spans residues 366-374 of influenza A nucleoprotein (A/PR/8/34) and is the immunodominant H-2Db-restricted CD8+ cytotoxic T-cell epitope in H-2b mice such as C57BL/6. It is one of the best-characterized model epitopes in antiviral immunology, routinely used to quantify CD8+ T-cell responses, in MHC tetramer staining, memory T-cell differentiation studies, vaccine design and mechanisms of protective immunity against influenza. influenza immunity, CD8 T cell responses, antiviral vaccines, mouse infection models, immunological memory Mouse H-2Db MHC class I (influenza NP-specific CD8+ T cells)

 

 

 

 

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