CAS 1223335-84-9 GAGGVGKSA

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CAS 1223335-84-9 GAGGVGKSA
Details
Octapeptide epitope GAGGVGKSA;
Category: Short peptide epitope / T-cell peptide.
Peptide Purity (HPLC) ≥95%
CAS No. 1223335-84-9
Structure Linear 8-mer (GAGGVGKSA)
Solubility Water/PBS
Storage Powder, −20°C, dry, light-protected
Category
Epitope Peptides
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Description

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Description GAGGVGKSA (position-3 Ala vs Asp in GADGVGKSA), used to probe how key residues affect MHC/TCR recognition; used for structure-activity and immune-recognition studies.

 

Product Basic Information Table

 

Product Standard English Name Product Abbreviation / Alias Function Tags (comma-separated) Core Structure Molecular Formula Exact Mass (Da) Average MW (Da) Salt Form Length (aa)
KRAS WT (10-18) GAGGVGKSA KRAS WT 10-18; GAGGVGKSA KRAS, wild-type, control peptide, neoantigen, epitope peptide H-Gly-Ala-Gly-Gly-Val-Gly-Lys-Ser-Ala-OH C28H50N10O11 702.37 702.77 以供应商COA为准(常用TFA盐) 9

 

Physicochemical Solubility & Storage Parameters

 

Product Code Appearance Long-term Storage Short-term Storage Solution Stability Solid Powder Stability
PEP-KRASWT-01 White to off-white powder -20 °C, dry, protected from light, sealed storage 2–8 °C for short-term storage; aliquot and freeze working solutions. No Cys/Met/Trp/Tyr; good stability. Contains Lys/Ser/Gly, good water solubility; soluble in water or a small amount of DMSO. Stable as powder under dry, sealed conditions.

 

Functional Description

 

Product Code Frontend Short Summary Detailed Biological Function Description Applicable Research Areas (comma-separated) Targets / Receptors
PEP-KRASWT-01 Wild-type KRAS 10–18 control peptide, used as a specificity control against the G12D mutant peptide in neoantigen studies. Human wild-type KRAS residues 10–18 (GAGGVGKSA), with the natural Gly at position 12 and no neoantigen mutation. As the wild-type control for the #7 G12D mutant peptide (GADGVGKSA), it is used to verify the recognition specificity of neoantigen-specific T cells, distinguish mutant- versus wild-type cross-reactivity, and serve as an MHC-binding affinity control. Tumor neoantigens; wild-type KRAS; control peptide; immunotherapy MHC class I

 

 

 

 

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