CAS 2032119-68-7 GADGVGKSA

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CAS 2032119-68-7 GADGVGKSA
Details
Octapeptide epitope GADGVGKSA;
Category: Short peptide epitope / T-cell peptide.
Peptide Purity (HPLC) ≥95%
CAS No. 2032119-68-7
Structure Linear 8-mer (GADGVGKSA)
Solubility Water/PBS
Storage Powder, −20°C, dry, light-protected
Category
Epitope Peptides
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Description

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Description GADGVGKSA binds MHC and is recognized by T cells, often used in autoimmunity/tumor epitope studies; used for epitope mapping, immune monitoring and tetramers.

 

Product Basic Information Table

 

Product Standard English Name Product Abbreviation / Alias Function Tags (comma-separated) Core Structure Molecular Formula Exact Mass (Da) Average MW (Da) Salt Form Length (aa)
KRAS G12D (10-18) GADGVGKSA KRAS G12D 10-18; GADGVGKSA KRAS, G12D, neoantigen, cancer vaccine, epitope peptide H-Gly-Ala-Asp-Gly-Val-Gly-Lys-Ser-Ala-OH C30H52N10O13 760.37 760.8 以供应商COA为准(常用TFA盐) 9

 

Physicochemical Solubility & Storage Parameters

 

Product Code Appearance Long-term Storage Short-term Storage Solution Stability Solid Powder Stability
PEP-KRASG12D-01 White to off-white powder -20 °C, dry, protected from light, sealed storage 2–8 °C for short-term storage; aliquot and freeze working solutions. No Cys/Met/Trp/Tyr; good chemical stability. Contains Asp/Lys/Ser, moderate-to-good water solubility; soluble in water or DMSO-assisted dissolution. Stable as powder under dry, sealed conditions.

 

Functional Description

 

Product Code Frontend Short Summary Detailed Biological Function Description Applicable Research Areas (comma-separated) Targets / Receptors
PEP-KRASG12D-01 9-mer neoantigen epitope from the KRAS G12D mutation, for tumor neoantigen vaccine and TCR-T/immunotherapy research. The 10–18 neoantigen peptide (GADGVGKSA) arises from the human KRAS Gly12→Asp (G12D) driver mutation; compared with wild-type GAGGVGKSA it has an additional Asp at position 3, creating a novel MHC-binding epitope. Widely used in pan-cancer (pancreatic, colorectal, lung, etc.) neoantigen vaccine design, neoantigen-specific T-cell induction, TCR screening and tumor immunotherapy research. Tumor neoantigens; KRAS G12D; cancer vaccines; immunotherapy; TCR-T MHC class I (tumor neoantigen presentation)

 

 

 

 

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