CAS 132326-72-8 InfluenzaNP(147-155)

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CAS 132326-72-8 InfluenzaNP(147-155)
Details
Influenza nucleoprotein residues 147-155 CTL epitope;
Category: Influenza NP classical CTL epitope / cross-strain conserved peptide.
Peptide Purity (HPLC) ≥95%
CAS No. 132326-72-8
Structure Linear 9-mer (influenza NP 147-155)
Solubility Water/PBS
Storage Powder, −20°C, dry, light-protected
Category
Epitope Peptides
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Description

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Description Influenza NP residues 147–155, an HLA-restricted CD8+ T epitope conserved across influenza A strains; used for influenza-specific memory CTL, cross-protective immunity and universal vaccines.

 

Product Basic Information Table

 

Product Standard English Name Product Abbreviation / Alias Function Tags (comma-separated) Core Structure Molecular Formula Exact Mass (Da) Average MW (Da) Salt Form Length (aa)
Influenza NP (147-155) Flu NP 147-155; NP147-155; TYQRTRALV; Influenza A NP (147-155); H-2Kd-restricted NP epitope CTL epitope, MHC-I, H-2Kd, influenza, nucleoprotein, viral immunology, CD8 T cell, vaccine research H-Thr-Tyr-Gln-Arg-Thr-Ala-Leu-Val-OH C48H82N16O14 1106.62 1107.28 以供应商 COA 为准(合成肽多为 TFA 盐,部分供应商提供醋酸盐/盐酸盐置换) 9

 

Physicochemical Solubility & Storage Parameters

 

Product Code Appearance Long-term Storage Short-term Storage Solution Stability Solid Powder Stability
PEP-FLUNP147-01 White to off-white powder -20 °C or below (recommended -20 °C ±5 °C), protected from light, dry and sealed; aliquot to avoid repeated freeze-thaw cycles 2–8 °C for short-term transport/storage (days to weeks) Contains Tyr/Trp-like aromatic residues; protect from light in solution. Prepare fresh before use; store working aliquots at -20 °C and avoid repeated freeze-thaw. A somewhat hydrophobic epitope with limited solubility in pure water; first dissolve in a small volume of DMSO, then dilute with water/buffer. Stable as powder; can be stored long-term under desiccation; degrades upon moisture absorption.

 

Functional Description

 

Product Code Frontend Short Summary Detailed Biological Function Description Applicable Research Areas (comma-separated) Targets / Receptors
PEP-FLUNP147-01 H-2Kd-restricted 9-mer CTL epitope from influenza nucleoprotein, for murine CD8+ T-cell response, vaccine and infection-immunity studies. Influenza NP (147-155) is the classic immunodominant epitope presented by the murine MHC class I molecule H-2Kd, derived from residues 147–155 of the nucleoprotein (NP) of influenza A/PR/8/34 (PR8) virus. It is specifically recognized by CD8+ cytotoxic T lymphocytes (CTLs) in PR8-infected mice, which then kill infected cells. It is one of the most widely used peptide–MHC tetramer antigen peptides in mouse influenza models, broadly applied to influenza vaccine development, cross-protective immunity, CTL response quantification (ELISPOT/ICC) and memory T-cell studies. Viral immunology; influenza vaccines; CTL/CD8+ T-cell immunity; MHC-I antigen presentation; infection and immune memory Murine H-2Kd (MHC class I); CD8+ T-cell TCR

 

 

 

 

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