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| Description | The residues 134–142 nonapeptide of EBV BRLF1 (Rta), an HLA-restricted CTL epitope; used for EBV-specific T-cell immunity, vaccine epitope screening and CTL assays. |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| Epstein-Barr Virus BRLF1 (134-142) | BRLF1 134-142, CEF30, ATIGTAMYK | EBV epitope peptide, HLA-A*11:01-restricted, CTL epitope, T cell detection | ATIGTAMYK (H-Ala-Thr-Ile-Gly-Thr-Ala-Met-Tyr-Lys-OH, linear 9-mer) | C42H70N10O13S | 954.48 | 955.14 | TFA salt (typical) | 9 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-BRLF1-01 | powder, white to off-white (AnaSpec CEF30, purity >=95% HPLC; CAS 216862-59-8) | Store frozen below -20 C, protected from light, dry and tightly sealed (Biosynth: store at <-15 C; stable approx. 3 years as powder) | Store at 4 C sealed and dry, use within 2-4 weeks; after reconstitution, aliquot and store at -20 C | Reconstitute in sterile water or DMSO; contains one Met residue prone to oxidation, so deoxygenate solutions, avoid oxidants, and aliquot to avoid repeated freeze-thaw; no Trp and low Tyr, no strict light protection required | powder is stable long-term (approx. 3 years) at -20 C, dry, light-protected and sealed; keep moisture-proof; Met is oxidation-sensitive, avoid prolonged air exposure |
Functional Description
| Product Code | Frontend Short Summary | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-BRLF1-01 | ATIGTAMYK, the HLA-A*11:01-restricted immunodominant CTL epitope from EBV immediate-early protein BRLF1 (Rta) residues 134-142, for EBV-specific CD8+ T cell detection and immune monitoring. | This peptide corresponds to residues 134-142 of the Epstein-Barr virus (HHV-4, B95-8) immediate-early replication and transcription activator BRLF1/Rta (UniProt P03209) and is an immunodominant HLA-A*11:01-restricted CD8+ CTL epitope (PDB 6JOZ reports the crystal structure of the peptide-HLA-A*11:01 complex). It is used to prepare peptide-MHC tetramers/pentamers, IFN-gamma ELISpot and intracellular cytokine staining for quantifying and characterizing EBV-specific T cells, and supports immune monitoring of EBV-associated malignancies such as nasopharyngeal carcinoma and post-transplant lymphoproliferative disorder (PTLD), TCR recognition studies and vaccine development. | Viral immunology, CD8+ T cell detection, Tetramer staining, Vaccine development | HLA-A*11:01 (MHC-I presentation); T cell receptor (TCR) |
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