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| Description | Influenza polymerase PA residues 224–233, an HLA/MHC-restricted CD8+ conserved epitope; used for influenza T-cell responses, memory and broad vaccines. |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| PA (224-233), Influenza Peptide (influenza A PA 224-233 epitope) | PA224-233; SSLENFRAYV; influenza PA H-2Db-restricted CTL epitope; PR8 strain; CAS 271573-27-4 | influenza virus, PA polymerase protein, CD8+ CTL epitope, H-2Db restricted, viral immunology, C57BL/6 mouse model | H-Ser-Ser-Leu-Glu-Asn-Phe-Arg-Ala-Tyr-Val-OH (linear 10-mer spanning residues 224-233 of the PA protein of influenza A/PR/8/34 (PR8, H1N1)) | C53H80N14O17 | 1184.58 | 1185.3 | TFA salt (explicitly marked 'Trifluoroacetate salt' by Solarbio; MCE supplies powder, free-base formula C53H80N14O17/MW 1185.29) | 10 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-PA224-01 | White to off-white powder | Store at -20℃, dry, sealed, protected from light (1 Tyr, guard against photo-oxidation) | Short-term at 2-8℃, sealed, dry, light-protected (days to 2 weeks); after reconstitution aliquot at -20℃ | Good water solubility (MCE: 10 mg/mL in H2O (8.44 mM), sonication-assisted; pH can be adjusted to 2 with 1 M HCl); also soluble in DMSO (ChemicalBook); protect from light (Tyr); prepare fresh, avoid repeated freeze-thaw | powder stable at -20℃ when dry, sealed and light-protected; keep dry, aliquot promptly after opening |
Functional Description
| Product Code | Frontend Short Summary | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Receptors |
| PEP-PA224-01 | An H-2Db-restricted CD8+ CTL epitope peptide SSLENFRAYV spanning residues 224-233 of the influenza A virus polymerase acidic protein (PA, PR8 strain); a routine reagent for T-cell response studies in C57BL/6 mouse influenza infection models. | PA(224-233) corresponds to residues 224-233 (SSLENFRAYV) of the polymerase acidic protein (PA) of influenza A virus A/Puerto Rico/8/34 (PR8, H1N1), a canonical CD8+ cytotoxic T lymphocyte (CTL) epitope in the C57BL/6 (H-2b) background (Belz et al., J Virol 2000;74:3486-3493; the title of the paper states H-2D(b)-restricted peptide). Applications: monitoring T-cell responses in influenza infection models (peptide-MHC tetramers, ELISPOT, intracellular cytokine staining), CTL epitope vaccine design and immune protection studies, and antigen presentation research. Note: some supplier pages (MCE) mislabel this peptide as 'polymerase 2 protein'; it is the PA protein. The MHC restriction is H-2Db (not H-2Kd), as established in the literature. | Viral immunology, influenza virus, T-cell epitopes, CD8+ CTL, vaccine development, mouse models | Presented by H-2Db (MHC class I); influenza PA-specific CD8+ TCR |
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