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| Description | Pigeon cytochrome c residues 88–104, a classic CD4+ T epitope model (single-residue differences drive MHC-II-restricted recognition); used for T-cell recognition and MHC-restriction studies. |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| Cytochrome c (pigeon) (88-104) (pigeon cytochrome c residues 88-104 heptadecapeptide) | Cytochrome c pigeon (88-104), KAERADLIAYLKQATAK, H-Lys-Ala-Glu-Arg-Ala-Asp-Leu-Ile-Ala-Tyr-Leu-Lys-Gln-Ala-Thr-Ala-Lys-OH | classical CD4+ T cell epitope, I-Ek-restricted, pigeon cytochrome c, TCR-MHC-peptide interaction model, immunogenicity species difference, Tyr-containing (light-protected), net charge +2, water-soluble | H-Lys-Ala-Glu-Arg-Ala-Asp-Leu-Ile-Ala-Tyr-Leu-Lys-Gln-Ala-Thr-Ala-Lys-OH (KAERADLIAYLKQATAK, linear 17-mer, free N-terminal amino group and free C-terminal carboxyl; contains 1 Tyr, no Cys/Met) | C84H144N24O25 | 1889.07 | 1890.22 | Not specified (commercial product is acetate salt; per Certificate of Analysis) | 17 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-CYTC88-01 | White powder (HPLC purity ≥95%) | Store desiccated and sealed below -20°C, protected from light; stable as powder; reconstituted aliquots protected from light stored at -20°C/-80°C | Carry short-term at 4°C sealed, desiccated and protected from light, use within 2-4 weeks; after reconstitution, aliquot and freeze, avoid repeated freeze-thaw | Net charge ~+2 (Lys x3 and Arg x1 versus Glu x1 and Asp x1), positively charged and water-soluble; can be reconstituted directly in water or PBS; contains 1 Tyr, keep protected from light; no Cys/Met, so no additional antioxidation/deoxygenation requirement | White powder (HPLC ≥95%), stored desiccated, light-protected and sealed at -20°C; protect from moisture and light; aliquot promptly after opening and keep in a desiccator |
Functional Description
| Product Code | Frontend Short Summary | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-CYTC88-01 | The C-terminal 88-104 heptadecapeptide KAERADLIAYLKQATAK of pigeon (Columba livia) cytochrome c; a classical I-Ek-restricted CD4+ T-cell epitope model used in TCR-MHC-peptide interactions and species-dependent immunogenicity studies. | This peptide corresponds to the C-terminal 17-mer KAERADLIAYLKQATAK of pigeon (Columba livia) cytochrome c (residues 88-104). It is a classical MHC class II-restricted CD4+ helper T-cell epitope model in immunology: in C3H/HeJ (H-2k) mice this 17-mer is presented by the I-Ek molecule and recognized by antigen-specific CD4+ T-cell hybridomas, serving as a standard tool peptide for studying TCR recognition, MHC class II-peptide complex formation, antigen presentation, and the immunogenicity differences caused by single-amino-acid substitutions among species cytochromes c. Order by the sequence KAERADLIAYLKQATAK and CAS 86579-06-8 (commercial product commonly supplied as acetate salt). | Basic immunology, CD4+ T cell epitope mapping, MHC class II presentation, TCR-peptide-MHC complex studies, species-dependent immunogenicity | MHC class II molecule I-Ek (presented on H-2k background); cytochrome c-specific CD4+ helper T cell receptors (TCR) |
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