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| Product name | CAS:1248559-53-6:Eptifibatide monoacetate |
| Description | Eptifibatide is a cyclic heptapeptide derived from snake venom disintegrin. It competitively blocks GP IIb/IIIa receptors on activated platelet surfaces, inhibits platelet aggregation and thrombus formation, and is applied in acute coronary syndrome, percutaneous coronary intervention and thrombosis mechanism research. |
| Peptide purity (HPLC, %) | 95%/98%/99% |
| Molecular formula | C₃₇H₅₃N₁₁O₁₁S₂ (monoacetate) |
| Molecular weight (Da) | 892.01 |
| Salt form | Monoacetate |
Products Description
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Full Amino Acid Sequence | Molecular Formula | Exact Mass (Da) | Average MW (Da) | N-terminal Modification | C-terminal Modification | Sequence Length (aa) |
| Eptifibatide monoacetate | Eptifibatide acetate; Integrilin; CAS 1248559-53-6 | GP IIb/IIIa receptor antagonist,Antiplatelet aggregation,Thrombosis inhibition,Acute coronary syndrome study,Disintegrin derived peptide,Cyclic heptapeptide | Mercaptopropionyl-homoarginine-glycine-aspartic acid-tryptophan-proline-cysteinamide (disulfide cyclized, contains RGD-like recognition sequence) | C₃₇H₅₃N₁₁O₁₁S₂ (monoacetate) | 891.34 | 892.01 | N-terminal mercaptopropionylation, no free amine | C-terminal amidation | 6 (core amino acids + Mpa terminus) |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage Conditions | Short-term Storage Conditions | Liquid Stability | Solid Powder Stability |
| PEP-EPT001 | white powder | Store at -20℃, strictly protected from light, sealed and dry, aliquoted. **Strictly prohibited from strong reducing agents** | Solid powder stable for 2 years at 2-8℃ sealed and dry; prepare aqueous solutions freshly before use | Stable for 72 h at 4℃; stable for 1 month at -20℃ in aliquots. **Good water solubility, freely soluble in water and physiological buffer**. Disulfide bridge is sensitive to strong reducing agents and prone to cleavage with activity loss. Tryptophan is prone to photooxidation | Stable for 3 years at -20℃ under dry & dark conditions |
Functional Description
| Product Code | Frontend Short Summary (for search list display) | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-EPT001 | Cyclic heptapeptide GP IIb/IIIa antagonist that competitively blocks the final platelet aggregation pathway with potent antithrombotic effect | Eptifibatide is a synthetic cyclic heptapeptide derived from rattlesnake venom disintegrin. The rigid cyclized structure maintains the active conformation of the RGD-like sequence, which binds with high affinity to glycoprotein IIb/IIIa (GP IIb/IIIa) receptors on activated platelet surfaces, competitively blocks fibrinogen binding to the receptor, thereby inhibits the common final pathway of platelet aggregation and exerts potent antithrombotic effect. Its action is reversible, platelet function recovers rapidly after discontinuation with low bleeding risk. This molecule serves as a classic tool peptide for thrombosis and hemostasis mechanism research, antiplatelet drug screening, acute coronary syndrome and peri-PCI pharmacological research, and is the active ingredient of widely used clinical intravenous antiplatelet drugs. | Thrombosis and hemostasis research,Antiplatelet drug development,Acute coronary syndrome study,Peri-PCI study,Platelet activation pathway study,Cardiovascular pharmacology research | Glycoprotein IIb/IIIa Receptor (GP IIb/IIIa); Final platelet aggregation pathway; Fibrinogen-receptor binding blockade |
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