Shanghai Sonyt Biotechnology Co., Ltd. is one of the leading manufacturers and suppliers of cas 151126-32-8 pramlintide in China, also supports custom service. Welcome to wholesale bulk high quality cas 151126-32-8 pramlintide from our factory. Contact us for more details.
| Product name | CAS:151126-32-8:Pramlintide |
| Description | Pramlintide is a synthetic human amylin analog with amino acid substitutions to reduce aggregation. It delays gastric emptying, suppresses glucagon secretion and increases satiety, applied in postprandial glucose control and metabolic mechanism research of type 1 and type 2 diabetes. |
| Peptide purity (HPLC, %) | 95%/98%/99% |
| Molecular formula | C₁₇₉H₂₈₈N₅₂O₅₅S₂ (free base) |
| Molecular weight (Da) | 3950.67 |
| Terminal modification | C-terminal amidation |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Full Amino Acid Sequence | Molecular Formula | Exact Mass (Da) | Average MW (Da) | N-terminal Modification | C-terminal Modification | Sequence Length (aa) |
| Pramlintide | Pramlintide; AC137; CAS 151126-32-8; Amylin analog | Amylin receptor agonist,Postprandial glucose control,Gastric emptying delay,Glucagon suppression,Diabetes research,Satiety enhancement | Lysine-cysteine-asparagine-threonine-alanine-threonine-cysteine-alanine-threonine-glutamine-arginine-leucine-alanine-asparagine-phenylalanine-leucine-valine-histidine-serine-serine-asparagine-asparagine-phenylalanine-glycine-proline-isoleucine-leucine-proline-proline-threonine-asparagine-valine-glycine-serine-asparagine-threonine-tyrosinamide | C₁₇₉H₂₈₈N₅₂O₅₅S₂ | 3948.12 | 3950.67 | Free amine | Amidation | 37 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage Conditions | Short-term Storage Conditions | Liquid Stability | Solid Powder Stability |
| PEP-PRA001 | white powder | Store at -20℃, strictly protected from light, sealed and dry, aliquoted; avoid repeated freeze-thaw cycles and vigorous shaking | Solid powder stable for 6 months at 2-8℃ sealed and dry; prepare aqueous solutions freshly before use | Stable for 48 h at 4℃; stable for 2 weeks at -20℃ in aliquots. **Good water solubility, freely soluble in water and dilute acetic acid**. Prone to amyloid aggregation and fibrillation upon prolonged storage; avoid high temperature, repeated freeze-thaw and vigorous shaking | Stable for 3 years at -20℃ under dry & dark conditions |
Functional Description
| Product Code | Frontend Short Summary (for search list display) | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-PRA001 | Amylin analog that controls postprandial glucose with insulin, delays gastric emptying and suppresses glucagon | Pramlintide is a synthetic analog engineered from the human amylin backbone. Proline and other amino acid substitutions significantly reduce the amyloid aggregation tendency of native amylin while retaining full receptor binding activity. It specifically activates central and peripheral amylin receptors and regulates glucose through three mechanisms: delays gastric emptying to reduce postprandial glucose absorption peak; suppresses excessive postprandial glucagon secretion to reduce hepatic glucose output; acts on the hypothalamic satiety center to reduce food intake. Combined with insulin, it stabilizes postprandial glucose fluctuations and reduces insulin dosage, serving as a core tool peptide for type 1/type 2 diabetes pathogenesis, postprandial glucose regulation and amylin pathway research. | Diabetes mechanism research,Postprandial glucose regulation study,Gastrointestinal motility research,Amylin pathway research,Antidiabetic drug development,Energy intake regulation research | Amylin Receptors (AMY1/AMY3); Gastric emptying regulatory pathway; Glucagon secretion suppression pathway; Central appetite regulatory pathway |
Hot Tags: cas 151126-32-8 pramlintide, China cas 151126-32-8 pramlintide manufacturers, suppliers, factory, 129954-34-3, 2381089-83-2, 910463-68-2, CAS 121062 08 6, CAS 129954 34 3, CAS 1566590 77 9
