CAS 85466-18-8 Thymocartin

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CAS 85466-18-8 Thymocartin
Details
CAS: 85466-18-8
Sequence: Arg-Lys-Asp-Val-Tyr (RKDVY, thymopoietin II fragment 32-36)
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Related documents

COA/MS/HPLC Report
Peptide Dissolution and Storage Guide
Category
Immunomodulatory Peptide / Thymus-derived Pentapeptide
Category
Pharmaceutical Peptides
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Description

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Product name CAS:85466-18-8:Thymocartin
Description Thymocartin is a synthetic pentapeptide derived from thymopoietin II. It promotes T lymphocyte differentiation and maturation, enhances cellular immune function, and regulates immune homeostasis. Applied in mechanism research of immunodeficiency, autoimmune diseases, tumor immunity and thymic function.
Peptide purity (HPLC, %) 95%/98%/99%
Molecular formula C₂₉H₄₉N₉O₉
Molecular weight (Da) 651.75
Terminal modifications Native free termini

 

Products Description

 

Product Standard English Name Product Abbreviation / Alias Function Tags (comma-separated) Full Amino Acid Sequence Molecular Formula Exact Mass (Da) Average MW (Da) N-terminal Modification C-terminal Modification Sequence Length (aa)
Thymocartin Thymocartin; Thymopoietin pentapeptide; CAS 85466-18-8 T cell differentiation promotion,Cellular immunity enhancement,Immunomodulation,Immunodeficiency study,Autoimmune disease study,Thymic function research Arginine-lysine-aspartic acid-valine-tyrosine C₂₉H₄₉N₉O₉ 651.37 651.75 Free amine, no modification Free carboxyl, no modification 5

 

Physicochemical Solubility & Storage Parameters

 

Product Code Appearance Long-term Storage Conditions Short-term Storage Conditions Liquid Stability Solid Powder Stability
PEP-TMC001 white powder Store at -20℃, sealed, dry & protected from light, aliquoted; avoid repeated freeze-thaw cycles Solid powder stable for 2 years at 2-8℃ sealed and dry; prepare aqueous solutions freshly before use Stable for 48 h at 4℃; stable for 2 weeks at -20℃ in aliquots. **Excellent water solubility, freely soluble in water and physiological buffer**. Unmodified short peptide easily degraded by peptidases with poor room-temperature stability Stable for 3 years at -20℃ under dry & dark conditions

 

Functional Description

 

Product Code Frontend Short Summary (for search list display) Detailed Biological Function Description Applicable Research Areas (comma-separated) Targets / Pathways
PEP-TMC001 Thymopoietin-derived pentapeptide that promotes T cell differentiation and maturation and bidirectionally regulates cellular immune function Thymocartin is a synthetic pentapeptide derived from residues 32-36 of thymopoietin II protein, retaining the core immunomodulatory activity of thymopoietin. It induces differentiation of bone marrow hematopoietic stem cells into T lymphocytes, promotes thymocyte maturation, enhances CD4+/CD8+ T cell function, and bidirectionally regulates immune homeostasis to correct both immune hyperactivity and immunodeficiency states. Its action does not depend on intact thymus tissue and can directly act on lymphocyte surface receptors to initiate T cell differentiation signaling pathways. This molecule serves as a classic tool peptide for thymic function research, immunodeficiency diseases, autoimmune diseases, and tumor immunotherapy adjuvant research, and can also be used for screening and evaluation of immunomodulatory drugs. Immunodeficiency research,Autoimmune disease study,Tumor immunity research,Thymic function study,T cell differentiation research,Immunomodulator development T cell differentiation signaling pathway; Thymocyte maturation pathway; Cellular immune regulatory pathway

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