Arg-Gly-Asp (RGD)

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Arg-Gly-Asp (RGD)
Details
Product Name:H-Arg-Gly-Asp-OH (Arg-Gly-Asp, RGD)
CAS No.:99896-85-2
Sequence:Arg-Gly-Asp (RGD)
Length:3 amino acids
Molecular Formula:C12H22N6O6
Molecular Weight:346.34 Da
Origin:Synthetic (minimal integrin-binding motif)
Purity:HPLC ≥95%
Related Documents
• COA/MS/HPLC Report
• Peptide Solubility and Storage Guide
Category
Cell Adhesion Peptides
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Description

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Description H-Arg-Gly-Asp-OH (RGD, CAS: 99896-85-2) is the core tripeptide sequence Arg-Gly-Asp recognized by integrins, molecular formula C12H22N6O6, MW 346.34 Da. The RGD motif is the core integrin-binding site of fibronectin, fibrinogen and other extracellular-matrix proteins; it inhibits platelet aggregation and fibrinogen binding, and is used in integrin-binding mechanism and biomaterial-surface-functionalization research.
Structure type Linear 3-mer (RGD minimal motif)
Solubility Readily soluble in water, PBS
Storage Powder -20C, dry, protected from light

 

Product Basic Information Table

 

Product Standard English Name Product Abbreviation / Alias Function Tags (comma-separated) Core Structure Molecular Formula Exact Mass (Da) Average MW (Da) Salt Form Length (aa)
Arg-Gly-Asp (RGD) RGD; Arg-Gly-Asp Integrin ligand, RGD tripeptide, cell adhesion, minimal integrin recognition motif Tripeptide Arg-Gly-Asp, minimal RGD integrin recognition core; net charge 0 (1 Arg vs 1 Asp); no Cys/Met/Trp; free acid C₁₂H₂₂N₆O₆ 346.16 346.34 游离酸 3

 

Physicochemical Solubility & Storage Parameters

 

Product Code Appearance Long-term Storage Short-term Storage Solution Stability Solid Powder Stability
PEP-RGD-01 White powder Store at -20°C, sealed, desiccated. No Cys/Met/Trp-chemically stable. Aliquot. 2–8°C for short-term; working solutions at -20°C; stable for shipping at ambient. Highly water-soluble small peptide; no Cys/Met/Trp oxidation concerns. Prepare fresh aqueous solutions. solid stable at -20°C, sealed and desiccated. Hygroscopic.

 

Functional Description

 

Product Code Frontend Short Summary Detailed Biological Function Description Applicable Research Areas (comma-separated) Targets / Pathways
PEP-RGD-01 Tripeptide Arg-Gly-Asp, the minimal RGD integrin recognition core that binds αvβ3 and other integrins; the classic short peptide in cell adhesion research. Arg-Gly-Asp (RGD) is the conserved tripeptide integrin-recognition sequence found in extracellular matrix proteins such as fibronectin and vitronectin. RGD directly binds multiple integrin heterodimers (especially αvβ3 and α5β1), mediating cell-matrix adhesion, migration, and proliferation. The RGD tripeptide is the minimal active unit of the RGD family, used as an integrin antagonist and cell adhesion control. Immobilizing RGD on biomaterial surfaces mimics ECM to promote cell adhesion. Integrin biology, cell adhesion, tissue engineering, drug delivery, tumor metastasis research αvβ3/α5β1 and other integrin receptors

 

 

 

 

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