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| Description | VLHDDLLEA binds MHC-I (HLA-A0201) and is recognized by specific TCRs; used for epitope-specific T-cell assays, MHC-tetramers and vaccine validation. |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| VLHDDLLEA | VLHDDLLEA, HLA-A*0201-restricted CTL epitope, H-Val-Leu-His-Asp-Asp-Leu-Leu-Glu-Ala-OH, CAS 204931-32-8 | MHC-I/HLA-A*0201,CTL epitope,CD8+ T cell,graft-versus-host disease GvHD,tumor/autoimmune epitope | VLHDDLLEA (H-Val-Leu-His-Asp-Asp-Leu-Leu-Glu-Ala-OH, linear 9-mer; HLA-A*0201-restricted nonamer epitope) | C45H73N11O16 | 1023.52 | 1024.14 | Free acid (per published formula; CAS 204931-32-8; MCE/TargetMol published MW 1024.13) | 9 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-VLHD-01 | White to off-white powder (purity >=95% HPLC; CAS 204931-32-8) | Store frozen below -20 C, dry, sealed and light-protected (single-use aliquots stable ~2-3 years) | Store at 4 C sealed and dry, use within 2-4 weeks; after reconstitution, aliquot and store at -20 C | Net charge -2 (2 Asp, 1 Glu acidic residues; 1 His); moderate water solubility; soluble in water or slightly basic buffer (pH 7-8); contains several hydrophobic residues (Val/Leu/Leu; 5/9), if poorly water-soluble use a small amount of DMSO first then dilute in buffer | powder stable long-term (~2-3 years) at -20 C, dry, light-protected and sealed; moisture-proof |
Functional Description
| Product Code | Frontend Short Summary | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-VLHD-01 | VLHDDLLEA (CAS 204931-32-8) is a nonamer epitope eluted from the human MHC-I molecule HLA-A*0201, recognized by HLA-A*0201-restricted cytotoxic T lymphocytes (CTLs), for graft-versus-host disease (GvHD) and CD8+ T-cell epitope studies. | VLHDDLLEA is a 9-mer peptide (CAS 204931-32-8; MCE/TargetMol published formula C45H73N11O16, MW 1024.13) that can be eluted from the human MHC complex HLA-A*0201. Presented in an HLA-A*0201-restricted epitope conformation, it is recognized by HLA-A*0201-restricted CD8+ cytotoxic T lymphocytes (CTLs). It is a tool peptide for graft-versus-host disease (GvHD) and transplant-immune T-cell epitope identification, CTL activation, and MHC-I tetramer construction; it can also be used for in vitro validation of tumor/self-antigen-derived HLA-I epitopes. | MHC-I/HLA-A*0201,CD8+ CTL epitope,graft-versus-host disease GvHD,transplant immunity,T cell tetramer | HLA-A*0201 (HLA-A0201) presentation complex; CD8+ cytotoxic T cell receptor (TCR) |
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