CAS 170294-35-6 Tyrosinase(192-200),humanmouse

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CAS 170294-35-6 Tyrosinase(192-200),humanmouse
Details
Human/mouse tyrosinase residues 192-200 melanoma epitope;
Category: Tumor differentiation antigen / melanoma CTL epitope.
Peptide Purity (HPLC) ≥95%
CAS No. 170294-35-6
Structure Linear 9-mer (tyrosinase 192-200, human/mouse)
Solubility Water, DMSO cosolvent, PBS
Storage Powder, −20°C, dry, light-protected
Category
Epitope Peptides
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Description

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Description Melanocyte differentiation antigen tyrosinase residues 192–200, a cross-reactive HLA-restricted CD8+ T epitope; used for melanoma autoimmunity, cancer vaccines and T-cell responses.

 

Product Basic Information Table

 

Product Standard English Name Product Abbreviation / Alias Function Tags (comma-separated) Core Structure Molecular Formula Exact Mass (Da) Average MW (Da) Salt Form Length (aa)
Tyrosinase (192-200), human/mouse Tyrosinase 192-200; SEIWRDIDF; Tyrosinase (192-200) (human, mouse); melanoma antigen epitope Tumor antigen, melanoma, tyrosinase, CTL epitope, HLA-B44, cancer vaccine, CD8 T cell, differentiation antigen H-Ser-Glu-Ile-Trp-Arg-Asp-Ile-Asp-Phe-OH C54H77N13O17 1179.56 1180.28 以供应商 COA 为准(合成肽多为 TFA 盐) 9

 

Physicochemical Solubility & Storage Parameters

 

Product Code Appearance Long-term Storage Short-term Storage Solution Stability Solid Powder Stability
PEP-TYRO192-01 White to off-white powder -20 °C ±5 °C, protected from light, dry and sealed; aliquot recommended 2–8 °C for short-term transport/storage Contains Trp; solutions must be protected from light to prevent oxidation. Slightly acidic (contains 2 Asp residues); soluble in water/dilute buffer. Prepare fresh; store working solutions at -20 °C protected from light. Stable as powder; store protected from light and dry.

 

Functional Description

 

Product Code Frontend Short Summary Detailed Biological Function Description Applicable Research Areas (comma-separated) Targets / Receptors
PEP-TYRO192-01 9-mer from human/mouse tyrosinase residues 192–200, an HLA-B44-restricted melanoma tumor-antigen CTL epitope. Tyrosinase (192-200) is a 9-mer derived from tyrosinase, a melanocyte differentiation antigen, recognized by HLA-B44-restricted cytotoxic T lymphocytes (CTLs). As a tumor-associated antigen (TAA) epitope, it is used in melanoma immunotherapy, peptide-vaccine development, CTL response monitoring and adoptive T-cell therapy research. The sequence is conserved between human and mouse at this segment, hence the product name is often marked human/mouse. Tumor immunology; melanoma; cancer vaccines; CTL/CD8+ T cells; HLA-B44 antigen presentation; adoptive immunotherapy HLA-B44 (HLA-B*44, MHC class I); CD8+ T-cell TCR

 

 

 

 

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