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| Description | PSA (kallikrein-family) residues 141–150, an HLA-restricted CD8+ T epitope relevant to prostate cancer; used for active immunotherapy, cancer vaccines and T-cell responses. |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| PSA1 (141-150) (human prostate-specific antigen / KLK3 residues 141-150, 10-mer) | PSA(141-150); FLTPKKLQCV; KLK3 141-150; prostate-specific antigen peptide; Creative Peptides R1645-2474; PEP-PSA1-01 | Prostate cancer immunotherapy, CTL epitope study, PSA/KLK3, antibody epitope mapping, proteomic reference peptide, free Cys (anti-oxidation), diagnostic reagent | Linear 10-mer, H-Phe-Leu-Thr-Pro-Lys-Lys-Leu-Gln-Cys-Val-OH (FLTPKKLQCV); residues 141-150 of mature human PSA (kallikrein-3/KLK3, UniProt P07288); contains one free cysteine; overlaps seamlessly with the known HLA-A*0201-restricted CTL epitope PSA 146-154 (KLQCVDLHV); C-terminal free acid; CAS 160215-60-1 | C55H93N13O13S | 1175.67 | 1176.49 | Not specified (typical TFA salt for synthetic peptides; per COA) | 10 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-PSA1-01 | White to off-white powder (synthetic peptide containing one free cysteine; CAS 160215-60-1, e.g. Creative Peptides R1645-2474) | Store sealed, dry and frozen at or below −20°C; powder stable for about 2 years; the free Cys readily oxidizes to intermolecular disulfide dimers - nitrogen protection and strictly oxygen-excluding sealing are recommended, and aliquot to avoid repeated freeze-thaw cycles; a possible TFA salt is hygroscopic, so keep dry. | Short-term storage at 2–8°C sealed and dry for about 2 weeks; aliquot working solutions and store at −20°C, prepare fresh, avoid repeated freeze-thaw and air exposure. | Moderately hydrophobic peptide (Phe/Leu/Val hydrophobic balanced by two Lys), soluble in water or pH 7.4 PBS; if poorly soluble, first co-dissolve with a small amount of DMSO then dilute. Because it contains one free Cys, it readily oxidizes in solution to intermolecular disulfide dimers - prepare fresh before use, aliquot into small portions, avoid prolonged room-temperature standing and repeated freeze-thaw; use nitrogen/anaerobic handling if necessary, and avoid oxidants and metal ions. | solid is stable for about 2 years at −20°C sealed and dry; the main degradation pathways are free-Cys oxidation (disulfide formation) and moisture uptake - store oxygen-protected, dry and away from oxidants; weigh promptly after opening and reseal under nitrogen. |
Functional Description
| Product Code | Frontend Short Summary | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-PSA1-01 | Synthetic linear peptide of human prostate-specific antigen PSA/KLK3 (141-150) (FLTPKKLQCV, 10-mer, free Cys), overlapping the HLA-A*0201-restricted CTL epitope PSA 146-154; for prostate cancer CTL epitope research, antibody epitope mapping and use as a proteomic reference peptide. | Prostate-specific antigen (PSA, also kallikrein-3/KLK3, UniProt P07288) is a serine protease secreted by prostatic epithelium and the classic serum diagnostic marker of prostate cancer. This product is a chemically synthesized linear peptide of residues 141–150 of mature PSA, FLTPKKLQCV, which overlaps seamlessly with the known HLA-A*0201-restricted CTL epitope PSA 146-154 (KLQCVDLHV, a classic epitope in prostate cancer T-cell immunotherapy research) and includes its core residues. This well-defined short peptide serves as a model tool for: CTL epitope identification and T-cell response detection in prostate cancer immunotherapy; epitope mapping of anti-PSA monoclonal/polyclonal antibodies; short-peptide substrates/references for PSA protein-protein interaction and enzymology studies; and standard reference peptides in mass-spectrometry proteomics method development. Because it contains one free cysteine, protect it from oxidation and intermolecular disulfide formation during handling and storage. |
Prostate cancer immunotherapy, CTL epitope research, antibody epitope mapping, proteomic reference peptide, PSA/KLK3 diagnostic reagents | PSA/KLK3 epitope; HLA-A*0201 (adjacent 146-154 epitope); anti-PSA antibody |
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