CAS 142479-13-8 CEF8,InfluenzaVirusNP(383-391)

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CAS 142479-13-8 CEF8,InfluenzaVirusNP(383-391)
Details
Influenza NP residues 383-391 from the CEF matrix;
Category: CEF pooled epitope / influenza NP memory epitope.
Peptide Purity (HPLC) ≥95%
CAS No. 142479-13-8
Structure Linear 9-mer (influenza NP 383-391, HLA-B8, CEF8)
Solubility Water/PBS; minor cosolvent
Storage Powder, −20°C, dry, light-protected
Category
Epitope Peptides
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Description

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Description Influenza NP residues 383–391 (canonical HLA-B8-restricted SRYWAIRTR), a common virus-specific memory CD8+ epitope in healthy adults; used for cellular-immunity assessment.

 

Product Basic Information Table

 

Product Standard English Name Product Abbreviation / Alias Function Tags (comma-separated) Core Structure Molecular Formula Exact Mass (Da) Average MW (Da) Salt Form Length (aa)
CEF8, Influenza Virus NP (383-391) Peptide Flu NP(383-391); SRYWAIRTR; HLA-B*2705 CTL epitope; CEF pool #8 Viral immunology, influenza virus, nucleoprotein NP, HLA-B*2705-restricted CTL epitope, CEF peptide pool SRYWAIRTR, linear free-acid 9-mer (N-term H, C-term OH) C54H85N19O13 1207.66 1208.38 TFA salt (per supplier COA) 9

 

Physicochemical Solubility & Storage Parameters

 

Product Code Appearance Long-term Storage Short-term Storage Solution Stability Solid Powder Stability
PEP-CEF8-01 White to off-white powder Store at -20°C, strictly protected from light, dry and sealed Short-term storage at 2-8°C, protected from light Basic peptide, readily soluble in water/slightly acidic buffer; light-sensitive (Trp/Tyr), prepare fresh, avoid repeated freeze-thaw Stable as light-protected powder

 

Functional Description

 

Product Code Frontend Short Summary Detailed Biological Function Description Applicable Research Areas (comma-separated) Targets / Pathways
PEP-CEF8-01 CEF pool member #8: the 9-mer SRYWAIRTR from influenza A virus nucleoprotein NP residues 383-391, a canonical HLA-B*2705-restricted CTL epitope linked to CTL immune escape. CEF8 corresponds to residues 383-391 (SRYWAIRTR) of the influenza A virus nucleoprotein (NP) and is an HLA-B*2705-restricted CD8+ cytotoxic T-lymphocyte epitope included in the CEF (CMV/EBV/influenza) positive-control peptide pool. Mutations within or near this epitope have been shown to alter the human influenza A virus-specific CTL response and contribute to viral escape from CTL immune surveillance (J Virol 2004;78:5216-22). It is used to study cross-protective influenza T-cell immunity, for HLA-B27-restricted CTL assays and as a CEF-pool positive control. Viral immunology, influenza vaccines, cross-protective T cells, CTL epitopes, immune-monitoring positive control Influenza NP(383-391) epitope presented by HLA-B*2705; influenza-specific CD8+ T cells

 

 

 

 

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