CAS 152274-91-4 LMP2A(426-434)

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CAS 152274-91-4 LMP2A(426-434)
Details
EBV latent membrane protein LMP2A canonical CD8+ T epitope;
Category: EBV latent membrane epitope / HLA-A0201 epitope.
Peptide Purity (HPLC) ≥95%
CAS No. 152274-91-4
Structure Linear 9-mer (LMP2A 426-434, CLGGLLTMV)
Solubility DMSO/water cosolvent, PBS
Storage Powder, −20°C, dry, light-protected
Category
Epitope Peptides
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Description

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Description LMP2A residues 426–434 (canonical CLGGLLTMV), one of the most used HLA-A0201-restricted EBV latent CTL epitopes; for EBV-specific T-cell culture, tumor immunology and vaccine validation.

 

Product Basic Information Table

 

Product Standard English Name Product Abbreviation / Alias Function Tags (comma-separated) Core Structure Molecular Formula Exact Mass (Da) Average MW (Da) Salt Form Length (aa)
Epstein-Barr Virus LMP2A (426-434) EBV LMP2A 426-434; CEF10; CLGGLLTMV EBV epitope peptide, HLA-A2 restricted, CTL epitope, T cell detection, Tumor immunology CLGGLLTMV (H-Cys-Leu-Gly-Gly-Leu-Leu-Thr-Met-Val-OH, linear 9-mer) C39H71N9O11S2 905.47 906.17 Trifluoroacetate (confirmed) 9

 

Physicochemical Solubility & Storage Parameters

 

Product Code Appearance Long-term Storage Short-term Storage Solution Stability Solid Powder Stability
PEP-LMP2A-01 white solid (TFA salt, vial filled with inert gas, purity >95% by HPLC) Store at ≤ -20°C, protected from light and moisture, sealed (Abbiotec: 1-year shelf life from dispatch) Store sealed and dry at 4°C for use within weeks; avoid repeated freeze-thaw Soluble in distilled water up to 2 mg/mL; use DMSO or acetonitrile to assist dissolution at higher concentrations (Abbiotec); aliquot reconstituted solution and store at -20°C; contains a free Cys thiol - protect from oxidation (degas, avoid strong oxidants in buffers) powder stable at -20°C, protected from moisture and light (hygroscopic - keep desiccated); avoid heat and repeated opening

 

Functional Description

 

Product Code Frontend Short Summary Detailed Biological Function Description Applicable Research Areas (comma-separated) Targets / Pathways
PEP-LMP2A-01 HLA-A2-restricted CTL epitope peptide of EBV latent membrane protein LMP2A (residues 426-434, CLGGLLTMV, CEF10); used for EBV-specific CD8+ T cell detection and tumor immunology research LMP2A is a membrane protein stably expressed during EBV latency and is an important target antigen in nasopharyngeal carcinoma, Hodgkin lymphoma and EBV-positive gastric cancer. This HLA-A2-restricted epitope induces strong IFN-gamma responses across multiple HLA-A*02 subtypes and is widely used for quantification of LMP2A-specific CD8+ T cells (tetramer staining, ELISpot, ICS), immunogenicity assessment of EBV peptide vaccines, and monitoring of tumor immunotherapeutic efficacy. EBV immunology, Virus-specific T cell detection, Tumor immunotherapy, Peptide vaccine development, Tetramer staining HLA-A*02:01 (MHC-I presentation); T cell receptor (TCR); antigen: LMP2A

 

 

 

 

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