CAS 156251-11-5 MART-1(27-35)(human)

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CAS 156251-11-5 MART-1(27-35)(human)
Details
Human melanoma antigen MART-1/Melan-A residues 27-35;
Category: Tumor differentiation antigen / HLA-A2 melanoma CTL epitope.
Peptide Purity (HPLC) ≥95%
CAS No. 156251-11-5
Structure Linear 9-mer (MART-1 27-35, AAGIGILTV, HLA-A2)
Solubility DMSO/water cosolvent, PBS
Storage Powder, −20°C, dry, light-protected
Category
Epitope Peptides
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Description

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Description Human MART-1/Melan-A residues 27–35 (canonical HLA-A*0201 AAGIGILTV), one of the most frequently recognized self tumor antigens in melanoma; used for melanoma vaccines and ACT.

 

Product Basic Information Table

 

Product Standard English Name Product Abbreviation / Alias Function Tags (comma-separated) Core Structure Molecular Formula Exact Mass (Da) Average MW (Da) Salt Form Length (aa)
MART-1 (27-35) human (AAGIGILTV, HLA-A*0201) AAGIGILTV; CAS 156251-11-5; human Melan-A/MART-1 27-35 epitope; Melan-A (27-35) immunodominant CTL epitope Tumor immunology, Melanoma, Therapeutic vaccine, CTL/TIL research, MHC tetramer, HLA-A*0201 H-Ala-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val-OH. From human melanocyte differentiation antigen Melan-A/MART-1 (MLANA) residues 27-35 (decamer 26-35 = EAAGIGILTV; dropping N-terminal Glu gives the 9-mer); all-aliphatic, highly hydrophobic; no Cys/Met/Trp/Tyr, no special light/oxidation requirement. C37H67N9O11 813.5 813.99 Free peptide / TFA salt (per supplier COA) 9

 

Physicochemical Solubility & Storage Parameters

 

Product Code Appearance Long-term Storage Short-term Storage Solution Stability Solid Powder Stability
PEP-MART127-01 White to off-white powder Store at -20°C, dry, sealed, light-protected; strongly hydrophobic epitope peptide; no Cys/Met/Trp/Tyr, no special oxidation-control requirement. Short-term storage at 2-8°C, dry and light-protected; avoid repeated freeze-thaw. Prepare fresh; all-aliphatic 9-mer with poor water solubility - must first dissolve in DMSO to a 5-10 mg/mL stock, then dilute in PBS/culture medium; store stock in aliquots at -20°C, light-protected. powder stable for 1-2 years at -20°C, sealed.

 

Functional Description

 

Product Code Frontend Short Summary Detailed Biological Function Description Applicable Research Areas (comma-separated) Targets / Pathways
PEP-MART127-01 Immunodominant HLA-A*0201 CTL epitope from human Melan-A/MART-1 (27-35), a 9-mer gold-standard melanoma-research peptide. The immunodominant HLA-A*0201-restricted epitope from human melanocyte differentiation antigen Melan-A/MART-1 residues 27-35, recognized by most melanoma-specific tumor-infiltrating lymphocytes; a gold-standard epitope for melanoma vaccine and CTL studies. Tumor immunology, Melanoma, Therapeutic vaccine, CTL/TIL research, MHC tetramer Presented on HLA-A*0201 to CD8+ T cells; recognized on Melan-A/MART-1-expressing melanoma cells.

 

 

 

 

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