CAS 168417-72-9 HBVSeq2aa:28-39

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CAS 168417-72-9 HBVSeq2aa:28-39
Details
HBV sequence-2 residues 28-39 epitope;
Category: HBV antigen / hepatitis-B T epitope.
Peptide Purity (HPLC) ≥95%
CAS No. 168417-72-9
Structure Linear 12-mer (HBV Seq2 28-39)
Solubility Water/PBS
Storage Powder, −20°C, dry, light-protected
Category
Epitope Peptides
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Description

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Description HBV sequence-2 residues 28–39, an HLA-restricted T-cell region; used for HBV-specific immunity, infection outcome and therapeutic vaccines.

 

Product Basic Information Table

 

Product Standard English Name Product Abbreviation / Alias Function Tags (comma-separated) Core Structure Molecular Formula Exact Mass (Da) Average MW (Da) Salt Form Length (aa)
HBV Seq2 aa:28-39 (hepatitis B virus surface antigen 28-39 dodecapeptide) HBsAg (28-39), IPQSLDSWWTSL, a-determinant region, H-Ile-Pro-Gln-Ser-Leu-Asp-Ser-Trp-Trp-Thr-Ser-Leu-OH HBV surface antigen epitope, a-determinant, B-cell epitope, diagnostic antigen region, Trp×2 (light-protection), serological assay reagent development H-Ile-Pro-Gln-Ser-Leu-Asp-Ser-Trp-Trp-Thr-Ser-Leu-OH (IPQSLDSWWTSL, linear 12-mer, free N-terminal amino group and free C-terminal carboxyl; contains 2 Trp, no Cys/Met) C67H97N15O20 1431.70 1432.60 Not specified (subject to COA) 12

 

Physicochemical Solubility & Storage Parameters

 

Product Code Appearance Long-term Storage Short-term Storage Solution Stability Solid Powder Stability
PEP-HBV2839-01 white to off-white Store desiccated, light-protected and sealed below -20°C; contains 2 Trp highly susceptible to photo-oxidation, keep strictly protected from light; powder stable for ~3 years; reconstituted aliquots can be stored light-protected at -80°C for ~1 year Store sealed, desiccated and light-protected at 4°C, use within 2-4 weeks; after reconstitution, aliquot and store light-protected at -20°C, avoid repeated freeze-thaw A short peptide with relatively good aqueous solubility; reconstitute directly with water or PBS; contains 2 Trp residues highly susceptible to photo-oxidation-strictly protect from light throughout reconstitution and storage (amber tube / foil wrap); no Cys/Met, so no additional antioxidation or dimerization requirement powder stable for ~3 years at -20°C when desiccated, light-protected and sealed; protect from moisture and light; aliquot promptly after opening, keep light-protected in a desiccator

 

Functional Description

 

Product Code Frontend Short Summary Detailed Biological Function Description Applicable Research Areas (comma-separated) Targets / Pathways
PEP-HBV2839-01 The 28-39 dodecapeptide IPQSLDSWWTSL of the hepatitis B virus surface antigen (HBsAg small S protein); located at the start of the highly conserved HBsAg 'a' determinant, a B-cell epitope / diagnostic-antigen region used for HBV serological reagent development, epitope mapping, and hepatitis B diagnostics/vaccine research. This peptide corresponds to residues 28-39 (IPQSLDSWWTSL) of the hepatitis B virus surface antigen (HBsAg small S protein; 'Seq2' in this catalog refers to the surface antigen). This segment lies at the beginning of the highly conserved HBsAg 'a' determinant, where the major subtypes adr/adw/ayw are essentially identical, constituting an important B-cell epitope and diagnostic-antigen region. According to supplier data (MedChemExpress, PeptideDB; CAS 168417-72-9), this product is used for HBV serological assay reagent development, HBsAg epitope mapping, anti-HBs antibody recognition studies, as well as hepatitis B diagnostic reagent and vaccine research. Note that it contains 2 Trp residues highly susceptible to photo-oxidation and must be kept light-protected throughout; 'Seq2' in this catalog refers to the surface antigen (HBsAg), whereas 'Seq1' refers to the core antigen (HBcAg); surface-antigen numbering varies slightly with genotype, so order by the sequence IPQSLDSWWTSL and CAS 168417-72-9. Viral hepatitis, HBsAg epitope mapping, B-cell epitope / diagnostic antigen, HBV serological assay reagent development, hepatitis B diagnostics and vaccine research HBsAg 'a' determinant; anti-HBs antibodies / B-cell epitope

 

 

 

 

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