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| Description | The residues 280–288 nonapeptide of EBV BMLF1 (SM post-transcriptional regulator), an HLA-restricted CD8+ CTL epitope; used for lytic-phase T-cell monitoring and epitope-vaccine studies. |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| Epstein-Barr Virus BMLF1 (280-288) | BMLF1 280-288, CEF11, GLCTLVAML | EBV epitope peptide, HLA-A*02:01-restricted, CTL epitope, T cell detection | GLCTLVAML (H-Gly-Leu-Cys-Thr-Leu-Val-Ala-Met-Leu-OH, linear 9-mer) | C40H73N9O11S2 | 919.49 | 920.20 | TFA salt (typical) | 9 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-BMLF1-01 | freeze-dried powder, white to off-white (AnaSpec CEF11, purity >=95% HPLC; CAS 183719-29-1) | Store frozen below -20 C, protected from light, dry and tightly sealed | Store at 4 C sealed and dry, use within 2-4 weeks; after reconstitution, aliquot and store at -20 C | Hydrophobic peptide (~67% hydrophobic residues): first dissolve in sterile DMSO (or acetonitrile), then dilute with aqueous buffer to working concentration; contains a free Cys thiol prone to oxidative dimerization, so deoxygenate, avoid oxidants, and if needed reconstitute under acidic/reducing conditions; Met is also oxidation-sensitive; aliquot to avoid repeated freeze-thaw | powder stored at -20 C, dry, light-protected and sealed; because the free Cys readily oxidizes and dimerizes, keep in an inert-atmosphere, moisture-proof sealed package and avoid air exposure |
Functional Description
| Product Code | Frontend Short Summary | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-BMLF1-01 | GLCTLVAML, the HLA-A*02:01-restricted immunodominant CTL epitope from EBV early protein BMLF1 (EB2) residues 280-288, widely used for quantifying EBV-specific CD8+ T cells. | This peptide is an immunodominant HLA-A*02:01-restricted CD8+ CTL epitope derived from the EBV early mRNA export protein BMLF1/EB2 (UniProt Q04360; IEDB Epitope ID 20788). Different literature sources number this segment as 259-267 / 280-288 / 300-308 due to strain and numbering-convention differences; the product sequence GLCTLVAML itself is confirmed by multiple sources. It is widely used for quantification and functional analysis of EBV-specific CD8+ T cells (ELISpot, intracellular cytokine staining, tetramer staining), immune monitoring of EBV-associated diseases (Burkitt lymphoma, Hodgkin lymphoma, nasopharyngeal carcinoma, infectious mononucleosis), and TCR-T target validation (anti-GLCTLVAML TCR-Jurkat reporter cell lines exist). | Viral immunology, CD8+ T cell detection, Tetramer staining, TCR-T target validation | HLA-A*02:01 (MHC-I presentation); T cell receptor (TCR) |
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