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| Description | Quazomotide, a defined-sequence synthetic peptide for therapeutic use, directed at immunomodulation/immunotherapy research; used for in vitro and in vivo efficacy evaluation per specification. |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| Quazamotide | Quazamotide (Quazomotide); RSDELVRHHNMHQRNMTKL; WT1-derived HLA-DR class II epitope; CAS 935395-33-8 | WT1,cancer vaccine,CD4 epitope,HLA-DR,tumor immunology | H-Arg-Ser-Asp-Glu-Leu-Val-Arg-His-His-Asn-Met-His-Gln-Arg-Asn-Met-Thr-Lys-Leu-OH (WT1 oncoprotein-derived MHC class II (HLA-DR) T-helper epitope, 19-mer; contains 2 Met - anti-oxidation essential (deoxygenation, inert atmosphere, light protection)) | C98H164N38O29S2 | 2401.2 | 2402.74 | Supplied as powder (free peptide), salt form not specified; per COA (synthetic peptides mostly TFA salt) | 19 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-QUAZAM-01 | White to off-white powder | Store at -20°C or below under inert atmosphere (N2), sealed, dry, light-protected (contains 2 Met - anti-oxidation is a priority); aliquot to avoid repeated freeze-thaw | 2–8°C, sealed, dry and light-protected, for days to weeks (short-term transport/storage) | Contains 2 Met: deoxygenate on reconstitution, avoid oxidants and light. Highly basic (4 Arg + 1 Lys + 2 His, plus 2 Asp/2 Glu) - good aqueous solubility; dissolve directly in water or dilute acetic acid, or use a small volume of DMSO for refractory material. Prepare fresh; aliquot at -20°C; avoid repeated freeze-thaw | powder stable for 1-2 years under N2, desiccated, light-protected and sealed; protect from moisture and oxidation; aliquot promptly after opening |
Functional Description
| Product Code | Frontend Short Summary | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-QUAZAM-01 | Quazamotide (RSDELVRHHNMHQRNMTKL), a WT1-derived HLA-DR class II epitope for cancer-vaccine CD4+ response studies. | Quazamotide is a Wilms tumor 1 (WT1) oncoprotein-derived MHC class II (HLA-DR) T-helper epitope peptide (19-mer) that elicits peptide-specific CD4+ T-helper responses to recognize and help eliminate WT1-positive tumor cells. As an active-immunization (therapeutic vaccine) candidate peptide, it is used in WT1 vaccine clinical trials and immune monitoring to assess CD4+ Th responses. | Tumor immunology,Therapeutic vaccines,WT1 tumor antigen,CD4+ helper T-cell epitopes | HLA-DR (MHC class II, multiple DR alleles); WT1-positive tumor cells; CD4+ T cells |
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