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| Description | HCV core residues 59–68, an HLA-restricted CD8+ T epitope; the core protein is a major CTL target; used for HCV immunity, viral clearance and vaccines. |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| HCV Core Protein (59-68) | HCV Core 59-68; RGRRQPIPKA; CAS 160187-72-4 | HCV,core protein,epitope mapping,viral immunology,basic peptide | H-Arg-Gly-Arg-Arg-Gln-Pro-Ile-Pro-Lys-Ala-OH (HCV core protein residues 59-68 (H77/genotype 1a reference sequence), N-terminal highly basic region; 10-mer, highly basic and hydrophilic, no Cys/Met/Trp/Tyr sensitive residues) | C50H91N21O12 | 1177.72 | 1178.41 | Supplied as free peptide powder, salt form not specified; highly basic sequences commonly supplied as acetate or TFA salt - per COA | 10 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-HCVC59-01 | White to off-white powder | Store at -20°C or below (recommended -20°C±5°C), dry, sealed; aliquot to avoid repeated freeze-thaw | 2–8°C, sealed and desiccated, for days to weeks (short-term transport/storage) | Highly basic (3 Arg + 1 Lys) hydrophilic 10-mer - excellent aqueous solubility; dissolve readily in water or dilute acid. No Cys/Met/Trp/Tyr sensitive residues - standard handling (light-protected storage still recommended). Prepare fresh; aliquot at -20°C; avoid repeated freeze-thaw | powder stable for >2 years when dry and sealed; protect from moisture; aliquot promptly after opening and keep with desiccant |
Functional Description
| Product Code | Frontend Short Summary | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-HCVC59-01 | HCV core protein 59-68 (RGRRQPIPKA), a basic 10-mer fragment for HCV antigenicity and epitope studies. | A synthetic peptide spanning HCV core protein residues 59-68 (RGRRQPIPKA, per the H77/genotype 1a reference sequence) located in the N-terminal highly basic region (part of the NLS motif PRGRRQPIPKARRP). Used for HCV core antigenicity, B-/T-cell epitope mapping and anti-HCV immune response studies, as well as core protein structure-function and interaction studies. (Note: the previously handled HCV core 107-114 = WGPNDPRR is a different region - do not confuse.) | Virology,HCV immunology,Epitope mapping,Core protein structure-function | HCV core protein (antigenicity study); no clearly restricting HLA allele reported |
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