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| Description | Kv3 voltage-gated potassium-channel-associated protein residues 567–585, a candidate autoantigen region linked to neurological autoimmunity (potassium-channel-antibody encephalopathy); used for autoantibody/auto-T-cell studies. |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| Kv3 Channel Containing Protein (567-585), rat Kv3.1b/KCNC1 | CKESPVIAKYMPTEAVRVT; no CAS number; GenScript RP20517 / TargetMol TP1491 catalog item; rat Kv3.1b (KCNC1, P25122) C-terminal 567-585 peptide | Ion channel research, Neuroscience, Potassium-channel antibody development, Basal ganglia / pallidal neurophysiology | H-Cys-Lys-Glu-Ser-Pro-Val-Ile-Ala-Lys-Tyr-Met-Pro-Thr-Glu-Ala-Val-Arg-Val-Thr-OH. Residues 567-585 of the intracellular C-terminal tail of rat Kv3.1b/KCNC1 (UniProt P25122); N-terminal Cys is native, not an added conjugation residue; contains 1 Cys + 1 Met + 1 Tyr; amphipathic, near-neutral, water-soluble. | C93H156N24O28S2 | 2121.1 | 2122.53 | Free peptide / typical TFA salt (not consistently annotated; per COA) | 19 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-KV3-01 | Off-white powder | Store at -20°C, dry and sealed; native N-terminal Cys plus Met/Tyr - store under nitrogen (inert atmosphere) to prevent oxidation, keep light-protected (amber/foil). | Short-term storage at 2-8°C, dry and light-protected; avoid repeated freeze-thaw. | Prepare fresh; amphipathic peptide reconstitutes directly in sterile water or buffer; degas the reconstitution solution (add reductant such as DTT if needed) to protect Cys/Met; aliquot and avoid freeze-thaw. | powder stable for 1-2 years at -20°C under nitrogen, sealed. |
Functional Description
| Product Code | Frontend Short Summary | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-KV3-01 | Residues 567-585 of rat Kv3.1b (KCNC1) C-terminal tail, a 19-mer commonly used as Kv3.1b antibody immunogen/control. | Corresponds to residues 567-585 of the intracellular C-terminal tail of rat Kv3.1b (KCNC1); widely used as the immunogen for Kv3.1b-specific antibodies and as a blocking/control peptide in WB and IHC. Kv3.1 channels mediate fast action-potential repolarization in fast-spiking GABAergic (e.g., parvalbumin-positive pallidal) neurons. | Ion channel research, Neuroscience, Potassium-channel antibody development, Basal ganglia / pallidal neurophysiology | C-terminal tail of the Kv3.1b (KCNC1) voltage-gated K+ channel; used as immunogen/control peptide, not a receptor ligand. |
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