CAS 203515-09-7 YLLEMLWRL

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CAS 203515-09-7 YLLEMLWRL
Details
Nonapeptide epitope YLLEMLWRL;
Category: MHC-I-restricted nonapeptide / T-cell epitope.
Peptide Purity (HPLC) ≥95%
CAS No. 203515-09-7
Structure Linear 9-mer (YLLEMLWRL)
Solubility Water, DMSO cosolvent, PBS
Storage Powder, −20°C, dry, light-protected
Category
Epitope Peptides
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Description

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Description YLLEMLWRL binds MHC-I and is recognized by TCRs; used for epitope-specific CD8+ T-cell assays, tetramers and recognition studies.

 

Product Basic Information Table

 

Product Standard English Name Product Abbreviation / Alias Function Tags (comma-separated) Core Structure Molecular Formula Exact Mass (Da) Average MW (Da) Salt Form Length (aa)
YLLEMLWRL (EBV LMP1 125-133, HLA-A*0201) YLLEMLWRL; CAS 203515-09-7; EBV LMP1 (B95-8) 125-133 peptide; EBV latent membrane protein 1 CTL epitope Tumor immunology, Viral immunology, CTL epitope identification, EBV-associated malignancy immunotherapy, MHC tetramer, HLA-A*0201 H-Tyr-Leu-Leu-Glu-Met-Leu-Trp-Arg-Leu-OH. Derived from EBV (strain B95-8) latent membrane protein 1 (LMP1) residues 125-133 (not EBNA-3A 458-466); free N-terminal amino / free C-terminal carboxyl; contains 1 Met + 1 Trp + 1 Tyr; highly hydrophobic. C60H93N13O13S 1235.67 1236.54 TFA salt / free peptide (not consistently annotated; per supplier COA) 9

 

Physicochemical Solubility & Storage Parameters

 

Product Code Appearance Long-term Storage Short-term Storage Solution Stability Solid Powder Stability
PEP-YLLEMLWRL-01 White to off-white powder (may be pale yellow due to Trp) Store at -20°C, dry, sealed, light-protected; Met/Trp/Tyr-containing - keep in amber/foil, deaerated, avoid oxidants. Short-term storage at 2-8°C, dry and light-protected; avoid repeated freeze-thaw. Prepare fresh; highly hydrophobic with poor water solubility. First dissolve in DMSO (or DMF) to a 5-10 mg/mL stock, then dilute in PBS/culture medium; store stock in aliquots at -20°C, light-protected. powder stable for 1-2 years at -20°C, sealed and light-protected.

 

Functional Description

 

Product Code Frontend Short Summary Detailed Biological Function Description Applicable Research Areas (comma-separated) Targets / Pathways
PEP-YLLEMLWRL-01 HLA-A*0201-restricted CTL epitope from EBV LMP1 (125-133), a 9-mer for EBV-associated tumor immunology research. HLA-A*0201-restricted CD8+ CTL epitope derived from Epstein-Barr virus latent membrane protein 1 (LMP1) residues 125-133; used for in vitro expansion of LMP1-specific CTLs, MHC-tetramer staining and immunotherapy studies in EBV-associated Hodgkin lymphoma, nasopharyngeal carcinoma and NK/T-cell lymphoma. Tumor immunology, Viral immunology, CTL epitope identification, EBV-associated malignancy immunotherapy, MHC tetramer Presented on HLA-A*0201 to CD8+ T cells; recognizes EBV LMP1-expressing target cells.

 

 

 

 

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