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| Product name | CAS:152685-85-3;Hemorphin-7 |
| Sequence | YPWTQRF |
| Three letter sequence | Tyr-Pro-Trp-Thr-Gln-Arg-Phe |
| Peptide purity (HPLC, %) | 95%/99% |
| Molecular formula | C49H64N12O11 |
| Molecular weight (Da) | 997.11 |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Amino Acid Full Name Sequence | Molecular Formula | Exact Molecular Weight (Da) | Average Molecular Weight (Da) | Terminal Modification - N-terminus | Terminal Modification - C-terminus | Sequence Length (aa) |
| Hemorphin-7 | #Hemorphin-7; CAS 152685-85-3; Hemoglobin-derived opioid peptide; Hemorphin heptapeptide | Endogenous opioid peptide, μ-opioid receptor ligand, Analgesic activity, Hemoglobin degradation fragment, Central analgesia, Vasodilation, Inflammation regulation, Peptide neuropharmacology | Val-Val-Tyr-Pro-Trp-Thr-Gln | C₄₁H₅₆N₁₂O₉ | 860.42 | 861 | Free amine, unmodified | Free carboxyl, unmodified | 7 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage Conditions | Short-term Storage Conditions | Liquid Stability | Solid Powder Stability |
| PEP-HEM001 | White powder | -20°C, sealed and light-proof, aliquot to avoid repeated freeze-thaw | 2~8°C, use within 1 month, prepare fresh & sterile-filter with 0.22μm membrane | Stable for 72 h at 4°C | Stable for 3 years at -20°C |
Functional Description
| Product Code | Frontend Short Summary (for search list display) | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Target / Receptor |
| PEP-HEM001 | Hemorphin-7 is an endogenous heptapeptide opioid ligand generated from hemoglobin β-chain proteolysis, selectively activates μ-opioid receptor with peripheral analgesic, vasodilatory and anti-inflammatory effects, classic tool peptide for endogenous opioid pathway research | Hemorphin-7 is an endogenous heptapeptide released via proteolytic cleavage of hemoglobin β-subunit, belonging to non-classical blood-derived opioid peptide family. Core biological functions: 1. Opioid receptor targeting: High selectivity binding & activation of μ-opioid receptor, producing central and peripheral analgesia with much lower addiction risk than morphine; 2. Cardiovascular regulation: Relaxes vascular smooth muscle, improves microcirculation and reduces peripheral vascular resistance; 3. Inflammatory & immune modulation: Suppresses pro-inflammatory cytokine release and alleviates inflammatory infiltration linked to neuropathic pain; 4. Tissue injury relief: Modulates pain conduction pathways for acute & chronic pain models. Widely applied in neuropharmacology, endogenous opioid system, pain mechanism, cardiovascular peptide research, inflammation immunity and hemoglobin metabolic pathway studies | Neuropharmacology, Pain mechanism research, Endogenous opioid pathway, Cardiovascular physiology, Inflammation & immune regulation, Hemoglobin metabolism, Analgesic peptide drug screening | μ-opioid receptor (MOR/OPRM1); Weak binding to δ-opioid receptor (DOR) |
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